2021
Calcium Signaling Regulates Autophagy and Apoptosis
Sukumaran P, Da Conceicao V, Sun Y, Ahamad N, Saraiva L, Selvaraj S, Singh B. Calcium Signaling Regulates Autophagy and Apoptosis. Cells 2021, 10: 2125. PMID: 34440894, PMCID: PMC8394685, DOI: 10.3390/cells10082125.Peer-Reviewed Original ResearchConceptsCell survivalOpposing functionCell death processMaintenance of cellular functionDepletion of Ca<sup>2+</sup>Pathogenesis of neurodegenerative diseasesPromote cell survivalNon-excitable cellsCytosolic Ca<sup>2+</sup> levelsCellular homeostasisCellular functionsAutophagy machineryER storesHuntington's diseaseDiverse functionsDeath processNeuronal developmentFunctional significanceNeurodegenerative diseasesPhysiological functionsNeurodegenerative conditionsApoptosisCellsHomeostasisImmune regulationIn Silico Exploration of the Potential Role of Acetaminophen and Pesticides in the Etiology of Autism Spectrum Disorder
Furnary T, Garcia-Milian R, Liew Z, Whirledge S, Vasiliou V. In Silico Exploration of the Potential Role of Acetaminophen and Pesticides in the Etiology of Autism Spectrum Disorder. Toxics 2021, 9: 97. PMID: 33925648, PMCID: PMC8146009, DOI: 10.3390/toxics9050097.Peer-Reviewed Original ResearchReactive oxygen speciesBiological processesEtiology of ASDCell death processSpecific metabolic pathwaysFunctional annotationInteraction networksCommon genesBiological pathwaysMetabolic pathwaysDatabase miningDeath processGenesGenetic associationOxygen speciesCarbohydrate metabolismNetwork topology analysisPesticide exposurePathwaySilico explorationPotential roleEnvironmental sourcesNeurodevelopmental disordersMetabolismTopology analysis
2009
tasselseed1 Is a Lipoxygenase Affecting Jasmonic Acid Signaling in Sex Determination of Maize
Acosta I, Laparra H, Romero SP, Schmelz E, Hamberg M, Mottinger JP, Moreno MA, Dellaporta SL. tasselseed1 Is a Lipoxygenase Affecting Jasmonic Acid Signaling in Sex Determination of Maize. Science 2009, 323: 262-265. PMID: 19131630, DOI: 10.1126/science.1164645.Peer-Reviewed Original ResearchConceptsJasmonic acidSex determinationPlant hormone jasmonic acidBisexual floral meristemHormone jasmonic acidMale flower developmentCell death processJasmonic acid concentrationsUnisexual floretsStamen developmentStaminate floretsFloral meristemFlower developmentMutant ts1Pistil primordiaInflorescencesDeath processMaizeDevelopmental cascadeFloretsLipoxygenase activityMeristemBiosynthesisAcidPrimordia
1999
Cell death and cell protection genes determine the fate of pistils in maize
Calderon-Urrea A, Dellaporta S. Cell death and cell protection genes determine the fate of pistils in maize. Development 1999, 126: 435-441. PMID: 9876173, DOI: 10.1242/dev.126.3.435.Peer-Reviewed Original ResearchConceptsPistil primordiaPistil cellsCell deathEar spikeletsSecondary floretsBisexual floral meristemCell death processFloral meristemFloral organsUnisexual flowersFunctional pistilsProtection genesDeath processPrimordiaSpikeletsFloretsPistilsGenesSexual maturationSelective eliminationMaizeNuclear degenerationEntire organCellsFate
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