2013
Neuroprotective Effect of Leukemia Inhibitory Factor on Antimycin A-Induced Oxidative Injury in Differentiated PC12 Cells
Han Y, Xu J, Li Z, Yang Z. Neuroprotective Effect of Leukemia Inhibitory Factor on Antimycin A-Induced Oxidative Injury in Differentiated PC12 Cells. Journal Of Molecular Neuroscience 2013, 50: 577-585. PMID: 23636893, DOI: 10.1007/s12031-013-0004-x.Peer-Reviewed Original ResearchConceptsLeukemia inhibitory factorOxidative injuryNeuroprotective effectsPC12 cellsInhibitory factorOxidative stressExerts neuroprotective effectsSuperoxide dismutase levelsElevated reactive oxygen species (ROS) levelsPC12 cell viabilityReactive oxygen species levelsHoechst 33342 stainingNeuron injuryDifferentiated PC12 cellsDiphenyltetrazolium bromide assayNeuroendocrine effectsNeurotrophic cytokinesPresence of LIFOxygen species levelsDismutase levelsInjuryAntioxidative effectsBromide assayDimethylthiazol-2Cell viability
2005
Evaluation of the cytotoxic and genotoxic effects of goniothalamin in leukemic cell lines
Rajab N, Hamid Z, Hassan H, Ali A, Din L, Inayat-Hussain S. Evaluation of the cytotoxic and genotoxic effects of goniothalamin in leukemic cell lines. Genes And Environment 2005, 27: 161. DOI: 10.3123/jems.27.161.Peer-Reviewed Original ResearchLeukemic cell linesGenotoxic effectsCEM-SS cellsCell linesHuman HL-60 promyelocytic leukemia cellsHuman leukemic cell linesTetrazolium bromide assayHL-60 promyelocytic leukemia cellsIC25 concentrationPromyelocytic leukemia cellsDNA damageLeukemic cellsLymphoblastic cellsLeukemia cellsAlkaline cometBromide assayMode of actionGenotoxic damageFurther studiesPrimary inductionOxidative damageIC50 valuesHL-60TreatmentCells
2004
Mevastatin inhibits ovarian theca–interstitial cell proliferation and steroidogenesis
Izquierdo D, Foyouzi N, Kwintkiewicz J, Duleba AJ. Mevastatin inhibits ovarian theca–interstitial cell proliferation and steroidogenesis. Fertility And Sterility 2004, 82: 1193-1197. PMID: 15474095, DOI: 10.1016/j.fertnstert.2004.03.037.Peer-Reviewed Original ResearchConceptsPolycystic ovary syndromeTheca-interstitial cellsCardiovascular riskCultured theca-interstitial cellsVascular smooth muscle proliferationSmooth muscle proliferationPotential therapeutic agentConcentration-dependent inhibitionDiphenyl tetrazolium bromide (MTT) assayConcentration-dependent decreaseDNA synthesisMesenchymal hyperplasiaOvary syndromeTetrazolium bromide assayMuscle proliferationMAIN OUTCOMECulture protein contentSpecific radioimmunoassayEffects of mevastatinT productionTherapeutic agentsMTT proliferationBromide assayDimethylthiazol-2Cell proliferationEffects of oxidants and antioxidants on proliferation of endometrial stromal cells
Foyouzi N, Berkkanoglu M, Arici A, Kwintkiewicz J, Izquierdo D, Duleba AJ. Effects of oxidants and antioxidants on proliferation of endometrial stromal cells. Fertility And Sterility 2004, 82: 1019-1022. PMID: 15474067, DOI: 10.1016/j.fertnstert.2004.02.133.Peer-Reviewed Original ResearchConceptsEndometrial stromal cellsVitamin E succinateStromal cellsOxidative stressHypoxanthine/xanthine oxidaseN-acetylcysteineModest oxidative stressXanthine oxidaseDose-dependent inhibitionDiphenyl tetrazolium bromide (MTT) assayDepletion of antioxidantsEndometrial stromaTetrazolium bromide assayReproductive ageMAIN OUTCOMEPathologic conditionsThymidine incorporationIncorporation assayMTT proliferationReactive oxygen speciesBromide assayDimethylthiazol-2EndometriosisComparable findingsProliferation
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