2015
Impaired LRP6-TCF7L2 Activity Enhances Smooth Muscle Cell Plasticity and Causes Coronary Artery Disease
Srivastava R, Zhang J, Go GW, Narayanan A, Nottoli TP, Mani A. Impaired LRP6-TCF7L2 Activity Enhances Smooth Muscle Cell Plasticity and Causes Coronary Artery Disease. Cell Reports 2015, 13: 746-759. PMID: 26489464, PMCID: PMC4626307, DOI: 10.1016/j.celrep.2015.09.028.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseLRP6 activityArtery diseaseObstructive coronary artery diseaseHigh-fat dietVascular smooth muscle cell differentiationMuscle cell plasticitySmooth muscle cell differentiationAtherosclerotic burdenMedial hyperplasiaCarotid injuryArterial diseaseVascular obstructionNeointima formationTherapeutic targetWnt3a administrationIntact WntVSMC differentiationKnockout backgroundDiseaseMiceVessel wallNon-canonical WntCoreceptor LRP6Cell plasticity
2006
Pulmonary Infarction
He H, Stein M, Zalta B, Haramati L. Pulmonary Infarction. Journal Of Thoracic Imaging 2006, 21: 1-7. PMID: 16538148, DOI: 10.1097/01.rti.0000187433.06762.fb.Peer-Reviewed Original ResearchConceptsPercent of patientsPleuritic chest painPulmonary infarctionPulmonary embolismDual blood supplyChest painCT findingsIschemic injuryParenchymal opacitiesBlood supplyExtent of PEClinical symptoms/signsAcute pulmonary embolismPulmonary vascular obstructionSymptoms/signsClot burdenPeripheral opacitiesConsecutive adultsHeart failureLower lobeMean ageVascular obstructionClinical correlatesImaging featuresFocal decreaseComputed Tomography Evaluation of Right Heart Dysfunction in Patients With Acute Pulmonary Embolism
He H, Stein M, Zalta B, Haramati L. Computed Tomography Evaluation of Right Heart Dysfunction in Patients With Acute Pulmonary Embolism. Journal Of Computer Assisted Tomography 2006, 30: 262-266. PMID: 16628044, DOI: 10.1097/00004728-200603000-00018.Peer-Reviewed Original ResearchConceptsRight heart dysfunctionAcute pulmonary embolismPulmonary embolismPulmonary vascular obstructionHeart dysfunctionSpecificity of CTClot burdenVascular obstructionRight ventricleInterventricular septumCT scanRight ventricular dilatationComputed Tomography EvaluationHours of CTSignificant differencesAdequate echocardiogramsTomography findingsConsecutive adultsMost patientsVentricular dilatationMean ageChest CTTomography evaluationNongated CTEmbolism
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply