2023
Aortic root allograft reoperations
Witten J, Umana-Pizano J, Houghtaling P, Insler J, Erten O, Nowicki E, Svensson L, Blackstone E, Unai S, Pettersson G. Aortic root allograft reoperations. Journal Of Thoracic And Cardiovascular Surgery 2023, 168: 440-452.e14. PMID: 37074251, DOI: 10.1016/j.jtcvs.2023.02.009.Peer-Reviewed Original ResearchConceptsStructural valve deteriorationAllograft reoperationInfective endocarditisValve deteriorationAllograft preservationAortic valve infective endocarditisRisk of reoperationReoperation techniquesOperative mortalityAllograft explantsSurgical approachExcellent outcomesAdverse eventsPerioperative eventsReoperationEndocarditisAllograftRisk factorsLower mortalityInvestigate outcomesMortalityOperative adverse eventsMorbidityPatientsOutcomes
2020
Bioprosthetic valve oversizing is associated with increased risk of valve thrombosis following TAVR
Simpson T, Tuohy C, Rajotte K, Golwala H, Fuss C, Song H, Zahr F, Chadderdon S. Bioprosthetic valve oversizing is associated with increased risk of valve thrombosis following TAVR. Catheterization And Cardiovascular Interventions 2020, 97: e411-e417. PMID: 32633055, DOI: 10.1002/ccd.29104.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve replacementAssociated with increased riskHypoattenuated leaflet thickeningValve thrombosisValve oversizingRisk of valve thrombosisTranscatheter heart valve thrombosisEvaluated consecutive patientsAortic valve replacementInitiation of anticoagulationSevere aortic stenosisSAPIEN 3 valveSTS risk scoreStructural valve deteriorationAssociated with increased risk of strokeStudy of patientsValve-in-valveRisk of strokeRate of strokeConsecutive patientsProspective trialsValve replacementAortic stenosisLeaflet thickeningValve deterioration
2019
Should All Low-risk Patients Now Be Considered for TAVR? Operative Risk, Clinical, and Anatomic Considerations
Siddique S, Gada H, Mumtaz M, Vora A. Should All Low-risk Patients Now Be Considered for TAVR? Operative Risk, Clinical, and Anatomic Considerations. Current Cardiology Reports 2019, 21: 161. PMID: 31781976, DOI: 10.1007/s11886-019-1250-5.Peer-Reviewed Original ResearchConceptsLow-risk patientsComposite endpoint of deathEndpoint of deathOptimal treatment choiceRandomized studyComposite endpointNon-inferior to surgeryTreatment choiceLow surgical risk patientsSurgical risk patientsPARTNER 3 trialSymptomatic aortic stenosisSymptomatic ASLack of long-term dataAortic stenosisFDA indicationRisk patientsPacemaker implantationValve deteriorationAnatomical factorsSummaryRecent trialsTAVRPatientsHigher incidenceProcedural considerations
2018
Hemodynamic Effects of Valve Asymmetry in Sapien 3 Transcatheter Aortic Valves.
Mangels DR, Siki M, Menon R, Bavaria J, Anwaruddin S, Giri J, Desai N, Szeto WY, Vallabhajosyula P, Herrmann HC. Hemodynamic Effects of Valve Asymmetry in Sapien 3 Transcatheter Aortic Valves. Journal Of Invasive Cardiology 2018, 30: 138-143. PMID: 29610444.Peer-Reviewed Original ResearchConceptsStructural valve deteriorationTranscatheter aortic valve replacementSAPIEN 3 valveParavalvular leakTransthoracic echocardiogramAortic insufficiencySAPIEN 3 transcatheter aortic valveAortic valve gradientSapien 3 prosthesisAortic valve replacementRetrospective cohort analysisTranscatheter aortic valveAI severityValve gradientAnnular calcificationHemodynamic effectsValve replacementValve deteriorationSmall prosthesisSingle institutionAortic valveAV gradientCohort analysisHigh incidenceSignificant differences
2015
Outcomes of Aortic Root Replacement After Previous Aortic Root Replacement: The “True” Redo Root
Jassar AS, Desai ND, Kobrin D, Pochettino A, Vallabhajosyula P, Milewski RK, McCarthy F, Maniaci J, Szeto WY, Bavaria JE. Outcomes of Aortic Root Replacement After Previous Aortic Root Replacement: The “True” Redo Root. The Annals Of Thoracic Surgery 2015, 99: 1601-1609. PMID: 25754965, DOI: 10.1016/j.athoracsur.2014.12.038.Peer-Reviewed Original ResearchConceptsAortic root replacementDe novo groupRedo root replacementRoot replacementNovo groupRedo groupPrevious aortic root replacementRedo aortic root replacementFirst-time sternotomyFull aortic root replacementLow perioperative morbidityStructural valve deteriorationRisk of complicationsPresence of infectionAortic reoperationHospital lengthLate deathsPerioperative deathsSternal infectionUnderwent reoperationMidterm survivalPerioperative morbidityRenal failureOverall mortalityValve deterioration
2000
Pregnancy outcomes and cardiac complications in women with mechanical, bioprosthetic and homograft valves
Sadler L, McCowan L, White H, Stewart A, Bracken M, North R. Pregnancy outcomes and cardiac complications in women with mechanical, bioprosthetic and homograft valves. BJOG An International Journal Of Obstetrics & Gynaecology 2000, 107: 245-253. PMID: 10688509, DOI: 10.1111/j.1471-0528.2000.tb11696.x.Peer-Reviewed Original ResearchConceptsMitral bioprosthetic valvesMitral mechanical valvesCardiac complicationsPregnancy loss rateAortic homograft valveHomograft valvesPregnancy outcomesBioprosthetic valvesMechanical valvesPregnancy lossHigher pregnancy loss rateHistorical cohort studyStructural valve deteriorationGreenlane HospitalSubcutaneous heparinCardiac outcomesCohort studyThromboembolic complicationsValve replacementValve deteriorationFirst trimesterComplicationsPregnancyMitral siteWarfarin
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