2025
The fungal microbiota modulate neonatal oxygen-induced lung injury
Martin I, Silverberg M, Abdelgawad A, Tanaka K, Halloran B, Nicola T, Myers E, Desai J, White C, Karabayir I, Akbilgic O, Tipton L, Gentle S, Ambalavanan N, Peters B, Vu L, Jain V, Lal C, Cormier S, Pierre J, Jilling T, Talati A, Willis K. The fungal microbiota modulate neonatal oxygen-induced lung injury. Microbiome 2025, 13: 24. PMID: 39871397, PMCID: PMC11773857, DOI: 10.1186/s40168-025-02032-x.Peer-Reviewed Original ResearchConceptsBronchopulmonary dysplasiaLung injury severityLung injuryDevelopment of bronchopulmonary dysplasiaSeverity of lung injuryAugmented lung injuryMorbidities of prematurityVery preterm infantsOxygen-induced lung injuryChronic lung diseaseIntestinal microbiomeMicrobiome of infantsPotential therapeutic strategyPreterm infantsNeonatal microbiomePremature infantsPremature neonatesInjury severityMurine modelNeonatal healthLung diseaseMouse modelTherapeutic strategiesLoss of function approachesFungal communities
2018
Differences in the fecal microbiota of neonates born at home or in the hospital
Combellick JL, Shin H, Shin D, Cai Y, Hagan H, Lacher C, Lin DL, McCauley K, Lynch SV, Dominguez-Bello MG. Differences in the fecal microbiota of neonates born at home or in the hospital. Scientific Reports 2018, 8: 15660. PMID: 30353125, PMCID: PMC6199260, DOI: 10.1038/s41598-018-33995-7.Peer-Reviewed Original ResearchConceptsHospital-born infantsTime of birthPro-inflammatory gene expressionBreast fed neonatesInfants 1 monthLong-term health implicationsHuman colon epithelial HT-29 cellsDay of birthVaginal swab samplesMonths of ageLower BacteroidesMaternal antibioticsNeonate's microbiomeNeonatal microbiomeVaginal sourcesHT-29 cellsWater birthVaginal microbiotaIntestinal microbiotaDay 1Vaginal samplesHospitalInfantsFecal microbiotaBabies
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