2021
Considering lead-time bias in evaluating the effectiveness of lung cancer screening with real-world data
Yang SC, Wang JD, Wang SY. Considering lead-time bias in evaluating the effectiveness of lung cancer screening with real-world data. Scientific Reports 2021, 11: 12180. PMID: 34108586, PMCID: PMC8190256, DOI: 10.1038/s41598-021-91852-6.Peer-Reviewed Original ResearchConceptsLead-time biasNational Lung Screening TrialStage shiftStage IALife expectancyCancer patientsLung cancerCalendar yearNationwide cancer registryBenefits of screeningLung cancer patientsReal-world studyLung cancer diagnosisMean life expectancyTomography screeningCancer RegistryLE gainsCancer screeningEarly diagnosisScreening TrialGeneral populationSame pathologyYounger agePathologyCancer diagnosis
2018
Systematic preoperative CT scan is associated with reduced risk of stroke in minimally invasive mitral valve surgery: A meta-analysis
Leonard JR, Henry M, Rahouma M, Khan FM, Wingo M, Hameed I, Di Franco A, Guy TS, Girardi LN, Gaudino M. Systematic preoperative CT scan is associated with reduced risk of stroke in minimally invasive mitral valve surgery: A meta-analysis. International Journal Of Cardiology 2018, 278: 300-306. PMID: 30563771, DOI: 10.1016/j.ijcard.2018.12.025.Peer-Reviewed Original ResearchConceptsPost-operative strokeInvasive mitral valve surgeryPooled event rateMitral valve surgeryCT screeningOperative mortalityValve surgeryMyocardial infarctionCT groupNew-onset renal failureLow operative mortalityPerioperative myocardial infarctionCardio-pulmonary bypassComputed Tomography ScreeningPreoperative CT scanRetrograde arterial perfusionInter-group comparisonAortic embolizationNew dialysisPerioperative strokeRenal failureTomography screeningArterial perfusionDecreased incidenceSurgical approachImproved discrimination between benign and malignant LDCT screening-detected lung nodules with dynamic over static 18F-FDG PET as a function of injected dose
Ye Q, Wu J, Lu Y, Naganawa M, Gallezot JD, Ma T, Liu Y, Tanoue L, Detterbeck F, Blasberg J, Chen MK, Casey M, Carson RE, Liu C. Improved discrimination between benign and malignant LDCT screening-detected lung nodules with dynamic over static 18F-FDG PET as a function of injected dose. Physics In Medicine And Biology 2018, 63: 175015. PMID: 30095083, PMCID: PMC6158045, DOI: 10.1088/1361-6560/aad97f.Peer-Reviewed Original ResearchConceptsPopulation-based input functionStandardized uptake valueImage-derived input functionLung nodulesClinical trialsTime-activity curvesLow-dose computed tomography (LDCT) screeningLung cancer mortality ratesIndeterminate lung nodulesComputed Tomography ScreeningF-FDG PETCancer mortality ratesStatic PET acquisitionVirtual clinical trialsScan durationTomography screeningFDG injectionPET scansMortality rateUptake valueAccurate diagnosisMalignant lung nodulesROC analysisPatient dataMalignant nodules
2015
Computed Tomography Screening for Lung Cancer
Milch H, Kaminetzky M, Pak P, Godelman A, Shmukler A, Koenigsberg T, Haramati L. Computed Tomography Screening for Lung Cancer. Journal Of Thoracic Imaging 2015, 30: 157-163. PMID: 25532712, DOI: 10.1097/rti.0000000000000123.Peer-Reviewed Original ResearchConceptsLung cancerCT screeningNational Lung Screening Trial eligibility criteriaOverall populationCT lung cancer screeningDiverse inner-city populationLung cancer prevalencePercent of patientsStage 1 diseaseLung cancer screeningCT lung cancerComputed Tomography ScreeningTrial eligibility criteriaInner-city populationElectronic medical recordsBaseline characteristicsCurrent smokersMortality benefitCT findingsTomography screeningObese populationStage IIATrial populationCancer screeningCancer prevalence
2014
Findings in asymptomatic HIV-infected patients undergoing chest computed tomography testing
Sigel K, Wisnivesky J, Shahrir S, Brown ST, Justice A, Kim J, Rodriguez-Barradas MC, Akgün KM, Rimland D, Hoo GW, Crothers K. Findings in asymptomatic HIV-infected patients undergoing chest computed tomography testing. AIDS 2014, 28: 1007-1014. PMID: 24401647, PMCID: PMC4018450, DOI: 10.1097/qad.0000000000000189.Peer-Reviewed Original ResearchConceptsNational Lung Screening TrialNLST criteriaCT findingsLung cancerCT scanHIV-Associated Lung Emphysema (EXHALE) studyAbnormal CT scansCD4 cell countChest CT findingsHigh-risk smokersAbnormal CT findingsLung cancer mortalityBalance of benefitsUninfected participantsUninfected veteransAsymptomatic HIVCD4 cellsAbnormal findingsTomography screeningUnadjusted riskHIV statusMultivariable analysisCancer mortalityChest CTClinical evaluation
2012
Current Status of Lung Cancer Screening
Ahmad U, Detterbeck FC. Current Status of Lung Cancer Screening. Seminars In Thoracic And Cardiovascular Surgery 2012, 24: 27-36. PMID: 22643659, DOI: 10.1053/j.semtcvs.2012.01.014.Peer-Reviewed Original Research
1994
Computed Tomography as a Screening Exam in Patients with Suspected Blunt Aortic Injury
Durham R, Zuckerman D, Wolverson M, Heiberg E, Luchtefeld W, Herr D, Shapiro M, Mazuski J, Salimi Z, Sundaram M. Computed Tomography as a Screening Exam in Patients with Suspected Blunt Aortic Injury. Annals Of Surgery 1994, 220: 699-704. PMID: 7979620, PMCID: PMC1234460, DOI: 10.1097/00000658-199411000-00015.Peer-Reviewed Original ResearchConceptsAortic injuryComputed tomography scanClinical courseBlunt traumaTomography scanNegative predictive value 99Blunt aortic injuryThoracic aortic injuryPatient's clinical courseSensitivity of CTPositive predictive valueAngiographic findingsTomography screeningCT manifestationsScreening examCT scanComputed tomographyPatientsPredictive valueInjuryAortographyValue 99ScansCTTrauma
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