2023
A Highly Sensitive and Specific Non‐Invasive Test through Genome‐Wide 5‐Hydroxymethylation Mapping for Early Detection of Lung Cancer
Ren Y, Zhang Z, She Y, He Y, Li D, Shi Y, He C, Yang Y, Zhang W, Chen C. A Highly Sensitive and Specific Non‐Invasive Test through Genome‐Wide 5‐Hydroxymethylation Mapping for Early Detection of Lung Cancer. Small Methods 2023, 8: e2300747. PMID: 37990399, DOI: 10.1002/smtd.202300747.Peer-Reviewed Original ResearchConceptsNon-small-cell lung cancerArea under the curveCell-free DNACell lung cancerBlood-based testLung cancerNon-small cell lung cancerLow-dose computed tomography screeningSmall cell lung cancerComputed Tomography ScreeningCell-free DNA samplesEarly detection of lung cancerNon-invasive testsDetect cell-free DNADetection of lung cancerDetect lung cancerPulmonary nodulesSerum biomarkersDiagnostic accuracyHealthy controlsCancerTissue originLungEarly detectionPatients
2018
Systematic preoperative CT scan is associated with reduced risk of stroke in minimally invasive mitral valve surgery: A meta-analysis
Leonard JR, Henry M, Rahouma M, Khan FM, Wingo M, Hameed I, Di Franco A, Guy TS, Girardi LN, Gaudino M. Systematic preoperative CT scan is associated with reduced risk of stroke in minimally invasive mitral valve surgery: A meta-analysis. International Journal Of Cardiology 2018, 278: 300-306. PMID: 30563771, DOI: 10.1016/j.ijcard.2018.12.025.Peer-Reviewed Original ResearchConceptsPost-operative strokeInvasive mitral valve surgeryPooled event rateMitral valve surgeryCT screeningOperative mortalityValve surgeryMyocardial infarctionCT groupNew-onset renal failureLow operative mortalityPerioperative myocardial infarctionCardio-pulmonary bypassComputed Tomography ScreeningPreoperative CT scanRetrograde arterial perfusionInter-group comparisonAortic embolizationNew dialysisPerioperative strokeRenal failureTomography screeningArterial perfusionDecreased incidenceSurgical approachImproved discrimination between benign and malignant LDCT screening-detected lung nodules with dynamic over static 18F-FDG PET as a function of injected dose
Ye Q, Wu J, Lu Y, Naganawa M, Gallezot JD, Ma T, Liu Y, Tanoue L, Detterbeck F, Blasberg J, Chen MK, Casey M, Carson RE, Liu C. Improved discrimination between benign and malignant LDCT screening-detected lung nodules with dynamic over static 18F-FDG PET as a function of injected dose. Physics In Medicine And Biology 2018, 63: 175015. PMID: 30095083, PMCID: PMC6158045, DOI: 10.1088/1361-6560/aad97f.Peer-Reviewed Original ResearchConceptsPopulation-based input functionStandardized uptake valueImage-derived input functionLung nodulesClinical trialsTime-activity curvesLow-dose computed tomography (LDCT) screeningLung cancer mortality ratesIndeterminate lung nodulesComputed Tomography ScreeningF-FDG PETCancer mortality ratesStatic PET acquisitionVirtual clinical trialsScan durationTomography screeningFDG injectionPET scansMortality rateUptake valueAccurate diagnosisMalignant lung nodulesROC analysisPatient dataMalignant nodules
2015
Computed Tomography Screening for Lung Cancer
Milch H, Kaminetzky M, Pak P, Godelman A, Shmukler A, Koenigsberg T, Haramati L. Computed Tomography Screening for Lung Cancer. Journal Of Thoracic Imaging 2015, 30: 157-163. PMID: 25532712, DOI: 10.1097/rti.0000000000000123.Peer-Reviewed Original ResearchConceptsLung cancerCT screeningNational Lung Screening Trial eligibility criteriaOverall populationCT lung cancer screeningDiverse inner-city populationLung cancer prevalencePercent of patientsStage 1 diseaseLung cancer screeningCT lung cancerComputed Tomography ScreeningTrial eligibility criteriaInner-city populationElectronic medical recordsBaseline characteristicsCurrent smokersMortality benefitCT findingsTomography screeningObese populationStage IIATrial populationCancer screeningCancer prevalence
2013
Health-related quality of life after surgical treatment in patients with non-small cell lung cancer: A systematic review
Poghosyan H, Sheldon L, Leveille S, Cooley M. Health-related quality of life after surgical treatment in patients with non-small cell lung cancer: A systematic review. Lung Cancer 2013, 81: 11-26. PMID: 23562675, DOI: 10.1016/j.lungcan.2013.03.013.Peer-Reviewed Original ResearchConceptsNon-small cell lung cancer survivorsHealth-related quality of lifeMental HR-QoLHealth-related qualityHR-QOLNon-small cell lung cancerQuality of lifePhysical functionIncreasing levels of dyspneaAssessment of HR-QOLSystematic review INTRODUCTIONAssociated with lower HR-QOLCell lung cancerLower HR-QOLLevel of dyspneaComputed Tomography ScreeningSurgical treatmentImprove symptom controlSurgical resectionContinued smokingSmoking cessationIII non-small cell lung cancerLung cancerPresence of comorbiditiesPrevalent symptoms
2012
The Impact of Computed Tomography Screening for Lung Cancer on Smoking Behaviors
Poghosyan H, Sheldon L, Cooley M. The Impact of Computed Tomography Screening for Lung Cancer on Smoking Behaviors. Cancer Nursing 2012, 35: 466-475. PMID: 22209869, DOI: 10.1097/ncc.0b013e3182406297.Peer-Reviewed Original ResearchConceptsLung cancer screeningQuit smokingCancer screeningIntegrative reviewSmoking cessationImpact of lung cancer screeningIntegrative review of literatureLung cancer symptomsOlder ageComputed Tomography ScreeningHigher self-efficacyLung cancerAssociated with older ageComputed tomographic screeningCancer symptomsCessation interventionsQuit ratesPotential screening testTeachable momentSmoking behaviorSelf-EfficacySmoking abstinenceSmokingRelevant articlesAbnormal CT findings
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