2021
Breast metastases from primary lung cancer: a retrospective case series on clinical, ultrasonographic, and immunohistochemical features
Wang B, Jiang Y, Li SY, Niu RL, Blasberg JD, Kaifi JT, Liu G, Wang ZL. Breast metastases from primary lung cancer: a retrospective case series on clinical, ultrasonographic, and immunohistochemical features. Translational Lung Cancer Research 2021, 0: 0-0. PMID: 34430360, PMCID: PMC8350075, DOI: 10.21037/tlcr-21-542.Peer-Reviewed Original ResearchPrimary lung cancerRetrospective case seriesBreast metastasisLung cancerCase seriesImmunohistochemical featuresCytokeratin 7Breast nodulesPrimary breast malignancyThyroid transcription factor-1Lung cancer metastasisAxillary lymphadenopathyClinical featuresLung metastasesImmunohistochemical findingsTranscription factor 1Ultrasonographic featuresBreast malignancyUltrasound featuresUltrasonographic characteristicsImmunohistochemical dataClinical practiceMetastasisNapsin A.Cancer
2016
TTF-1 Expression in Rectal Adenocarcinoma: A Case Report and Review of the Literature
Belalcazar A, Krishnamurti U, Shaib W. TTF-1 Expression in Rectal Adenocarcinoma: A Case Report and Review of the Literature. Case Reports In Oncology 2016, 9: 747-751. PMID: 27990111, PMCID: PMC5156892, DOI: 10.1159/000450973.Peer-Reviewed Original ResearchRectal adenocarcinomaCase reportTTF-1Primary lung adenocarcinomaThyroid transcription factor-1Year retrospective studyTTF-1 expressionLung metastasesRetrospective studyTranscription factor 1Colorectal adenocarcinomaLung adenocarcinomaAdenocarcinomaColon adenocarcinomaMedical literatureTumor samplesSpecific markersFactor 1The Impact of the Fourth Edition of the WHO Classification of Lung Tumours on Histological Classification of Resected Pulmonary NSCCs
Micke P, Mattsson J, Djureinovic D, Nodin B, Jirström K, Tran L, Jönsson P, Planck M, Botling J, Brunnström H. The Impact of the Fourth Edition of the WHO Classification of Lung Tumours on Histological Classification of Resected Pulmonary NSCCs. Journal Of Thoracic Oncology 2016, 11: 862-872. PMID: 26872818, DOI: 10.1016/j.jtho.2016.01.020.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaAdultAgedAged, 80 and overBiomarkers, TumorCarcinoma, Large CellCarcinoma, Non-Small-Cell LungCarcinoma, Squamous CellFemaleHumansImmunohistochemistryLung NeoplasmsMaleMiddle AgedNeoplasm StagingNeuroendocrine TumorsPrognosisSmall Cell Lung CarcinomaWorld Health OrganizationConceptsNon-small cell carcinomaPulmonary non-small cell carcinomaCell carcinomaWHO classificationLung tumorsFourth EditionWorld Health Organization classificationLarge cell carcinomaSquamous cell carcinomaThyroid transcription factor-1Cases of adenocarcinomaMost patientsHistological typeAdenocarcinoma groupAdenocarcinomatous differentiationOrganization classificationLung cancerNeuroendocrine tumorsTranscription factor 1Napsin AHistological classificationIHC markersHistopathological classificationImmunohistochemical stainingIHC staining
2012
PDX-1, CDX-2, TTF-1, and CK7
Chan ES, Alexander J, Swanson PE, Jain D, Yeh MM. PDX-1, CDX-2, TTF-1, and CK7. The American Journal Of Surgical Pathology 2012, 36: 737-743. PMID: 22498824, DOI: 10.1097/pas.0b013e31824aba59.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overBiomarkers, TumorCDX2 Transcription FactorDiagnosis, DifferentialDNA-Binding ProteinsFemaleHomeodomain ProteinsHumansImmunohistochemistryIntestinal NeoplasmsKeratin-20Keratin-7Liver NeoplasmsLung NeoplasmsMaleMiddle AgedNeuroendocrine TumorsPancreatic NeoplasmsSensitivity and SpecificitySingle-Blind MethodTrans-ActivatorsTranscription FactorsConceptsGI neuroendocrine tumorsThyroid transcription factor-1Pancreatic neuroendocrine tumorsBronchopulmonary neuroendocrine tumorsMetastatic neuroendocrine tumorsPrimary neuroendocrine tumorNeuroendocrine tumorsCDX-2PDX-1Primary siteMetastatic pancreatic neuroendocrine tumorsPrimary pancreatic neuroendocrine tumorsDuodenal neuroendocrine tumorsΒ-cell functionSimilar morphologic featuresPancreatic duodenal homeobox-1Good overall diagnostic accuracyOverall diagnostic accuracyDuodenal homeobox 1Radiologic dataTranscription factor 1IHC panelImmunohistochemical markersIHC analysisKeratin 7
2011
Molecular classification of nonsmall cell lung cancer using a 4‐protein quantitative assay
Anagnostou VK, Dimou AT, Botsis T, Killiam EJ, Gustavson MD, Homer RJ, Boffa D, Zolota V, Dougenis D, Tanoue L, Gettinger SN, Detterbeck FC, Syrigos KN, Bepler G, Rimm DL. Molecular classification of nonsmall cell lung cancer using a 4‐protein quantitative assay. Cancer 2011, 118: 1607-1618. PMID: 22009766, DOI: 10.1002/cncr.26450.Peer-Reviewed Original Research
2008
Thyroid Transcription Factor 1 Is an Independent Prognostic Factor for Patients With Stage I Lung Adenocarcinoma
Anagnostou VK, Syrigos KN, Bepler G, Homer RJ, Rimm DL. Thyroid Transcription Factor 1 Is an Independent Prognostic Factor for Patients With Stage I Lung Adenocarcinoma. Journal Of Clinical Oncology 2008, 27: 271-278. PMID: 19064983, DOI: 10.1200/jco.2008.17.0043.Peer-Reviewed Original ResearchConceptsThyroid transcription factor-1Stage I lung adenocarcinomaTTF1 expressionTranscription factor 1Lung adenocarcinomaStage IIndependent lower riskMedian overall survivalProtein expressionIndependent prognostic factorPotential prognostic parametersSubgroup of patientsFactor 1Overall survivalPrognostic factorsPatient survivalPrognostic parametersPrognostic stratificationLung cancerFavorable outcomeSitu protein expressionIndependent cohortLower riskPatientsAdenocarcinoma
2001
Expression of thyroid transcription factor-1 and other markers in sclerosing hemangioma of the lung.
Illei P, Rosai J, Klimstra D. Expression of thyroid transcription factor-1 and other markers in sclerosing hemangioma of the lung. Archives Of Pathology & Laboratory Medicine 2001, 125: 1335-9. PMID: 11570910, DOI: 10.5858/2001-125-1335-eottfa.Peer-Reviewed Original ResearchConceptsThyroid transcription factor-1Sclerosing hemangiomaTranscription factor 1Tumor cellsPulmonary epitheliumThyroid transcription factor-1 positivityFactor 1Expression of thyroid transcription factor-1Pale cellsLining cellsSolid areasPulmonary sclerosing hemangiomaCell typesPan-epithelialEpithelial tumorsFocal stainingEMA stainingVascular neoplasmPapillary structuresEpithelial markersAlveolar epitheliumHemangiomaNeoplastic cellsStaining intensityTumorExpression of Thyroid Transcription Factor-1, Surfactant Proteins, Type I Cell–associated Antigen, and Clara Cell Secretory Protein in Pulmonary Hypoplasia
Zhou H, Morotti R, Profitt S, Langston C, Wert S, Whitsett J, Greco M. Expression of Thyroid Transcription Factor-1, Surfactant Proteins, Type I Cell–associated Antigen, and Clara Cell Secretory Protein in Pulmonary Hypoplasia. Pediatric And Developmental Pathology 2001, 4: 364-371. PMID: 11441338, DOI: 10.1007/s10024001-0002-9.Peer-Reviewed Original ResearchConceptsClara cell secretory proteinPulmonary hypoplasiaWeeks gestational ageTranscription factor 1Thyroid transcription factor-1Cell-associated antigensSecretory proteinsTTF-1Surfactant proteinsHomeodomain transcription factorGestational ageFactor 1Distal lung developmentProximal-distal axisEpithelial gene expressionDistal lung parenchymaNormal fetal lungTranscription factorsFinal common pathwayLung organogenesisExpression patternsGene expressionImmunolocalization patternsProteinLung parenchyma
2000
Expression of Thyroid Transcription Factor-1, Surfactant Proteins, Type I Cell–associated Antigen, and Clara Cell Secretory Protein in Pulmonary Hypoplasia
Zhou H, Morotti R, Profitt S, Langston C, Wert S, Whitsett J, Greco M. Expression of Thyroid Transcription Factor-1, Surfactant Proteins, Type I Cell–associated Antigen, and Clara Cell Secretory Protein in Pulmonary Hypoplasia. Pediatric And Developmental Pathology 2000, 4: 364-371. DOI: 10.1007/s10024-001-0002-9.Peer-Reviewed Original ResearchClara cell secretory proteinTranscription factor 1Pulmonary hypoplasiaWeeks gestational ageThyroid transcription factor-1Cell-associated antigensSecretory proteinsTTF-1Surfactant proteinsHomeodomain transcription factorGestational ageFactor 1Distal lung developmentProximal-distal axisEpithelial gene expressionDistal lung parenchymaNormal fetal lungTranscription factorsFinal common pathwayLung organogenesisExpression patternsGene expressionNKx2 familyImmunolocalization patternsProteinExpression of Thyroid Transcription Factor-1 in Congenital Cystic Adenomatoid Malformation of the Lung
Morotti R, Gutierrez M, Askin F, Profitt S, Wert S, Whitsett J, Greco M. Expression of Thyroid Transcription Factor-1 in Congenital Cystic Adenomatoid Malformation of the Lung. Pediatric And Developmental Pathology 2000, 3: 455-461. PMID: 10890930, DOI: 10.1007/s100240010092.Peer-Reviewed Original ResearchConceptsCongenital cystic adenomatoid malformationCCAM type 1TTF-1 expressionCystic adenomatoid malformationThyroid transcription factor-1Gestational ageTTF-1Type 1Adenomatoid malformationTranscription factor 1Fetal lungAlveolar cell markersBasal cellsEpithelial cellsWeeks gestational ageTTF-1 stainingType 4Factor 1Bronchiolar basal cellsDistal air spacesAlveolar type II cellsType I cellsEarly lung developmentType II cellsCCAM cases
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