2017
Maternal prenatal anxiety and child COMT genotype predict working memory and symptoms of ADHD
O'Donnell KJ, Glover V, Lahti J, Lahti M, Edgar RD, Räikkönen K, O'Connor TG. Maternal prenatal anxiety and child COMT genotype predict working memory and symptoms of ADHD. PLOS ONE 2017, 12: e0177506. PMID: 28614354, PMCID: PMC5470664, DOI: 10.1371/journal.pone.0177506.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAnxietyAttention Deficit Disorder with HyperactivityCatechol O-MethyltransferaseChildFemaleGene-Environment InteractionGenotypeHumansLongitudinal StudiesMaleMemory, Short-TermMothersPolymorphism, Single NucleotidePregnancyPrenatal Exposure Delayed EffectsProspective StudiesSelf ReportConceptsMaternal prenatal anxietySymptoms of ADHDPrenatal anxietyChildren's symptomsSelf-report measuresInter-individual differencesRs4680 genotypeIndividual differencesHyperactivity symptomsChildren's responsesADHDDevelopmental outcomesCOMT genotypeAnxietyAge 8 yearsMemoryVal/Val genotypeVal/ALSPAC cohortChild neurodevelopmentYears of ageFunctional genetic variationVal genotypeCOMTGene-environment interactions
2014
Guanfacine extended release for the treatment of attention-deficit/hyperactivity disorder in children and adolescents
Connor DF, Arnsten A, Pearson GS, Greco GF. Guanfacine extended release for the treatment of attention-deficit/hyperactivity disorder in children and adolescents. Expert Opinion On Pharmacotherapy 2014, 15: 1601-1610. PMID: 24992513, DOI: 10.1517/14656566.2014.930437.Peer-Reviewed Original ResearchConceptsAttention-deficit/hyperactivity disorderHyperactivity disorderSymptoms of ADHDEvidence-based treatmentsTraumatic stressBehavioral dysregulationADHD studiesSmall effect sizesPrefrontal cortexAdolescents 6Behavioral conditionsAdolescentsEffect sizeGXRPsycINFO databasesGuanfacinePsychostimulantsShire PharmaceuticalsOpen trialChildrenPotential promiseSecond-line treatmentDisordersAntihypertensive agentsAdrenoreceptor agonist
2010
Social Adjustment Among Taiwanese Children with Symptoms of ADHD, ODD, and ADHD Comorbid with ODD
Tseng WL, Kawabata Y, Gau SS. Social Adjustment Among Taiwanese Children with Symptoms of ADHD, ODD, and ADHD Comorbid with ODD. Child Psychiatry & Human Development 2010, 42: 134-151. PMID: 20886286, DOI: 10.1007/s10578-010-0204-3.Peer-Reviewed Original ResearchConceptsSocial adjustment problemsSocial adjustmentAdjustment problemsMothers' reportsSocial Adjustment InventorySymptoms of ADHDConners' Rating ScalesSchool-based sampleADHD ComorbidODD symptomsAdjustment InventoryRating ScaleADHDNinth gradersTaiwanese childrenSocial problemsGreater levelsChildrenNormal controlsGradersAdjustmentAdolescentsSchoolsPeersComorbid
2007
The role of abnormal neural oscillations in the pathophysiology of co-occurring Tourette syndrome and attention-deficit/hyperactivity disorder
Sukhodolsky DG, Leckman JF, Rothenberger A, Scahill L. The role of abnormal neural oscillations in the pathophysiology of co-occurring Tourette syndrome and attention-deficit/hyperactivity disorder. European Child & Adolescent Psychiatry 2007, 16: 51-59. PMID: 17665283, DOI: 10.1007/s00787-007-1007-3.Peer-Reviewed Original ResearchConceptsAttention-deficit/hyperactivity disorderTourette syndromeAbnormal neural oscillationsOscillatory activityHyperactivity disorderAbnormal oscillatory activityThalamo-cortical circuitsSymptoms of ADHDNeural oscillationsNeural oscillatory activityBasal gangliaFunctional abnormalitiesNormal brainThalamocortical regionsThalamocortical oscillationsCortical regionsTransient hyperpolarizationPrefrontal cortexNeural activityNeural communicationPathophysiologyMotor controlSyndromeBrainDisorders
1988
Desipramine Treatment of Boys with Attention-Deficit Hyperactivity Disorder and Tics: Preliminary Clinical Experience
RIDDLE M, HARDIN M, CHO S, WOOLSTON J, LECKMAN J. Desipramine Treatment of Boys with Attention-Deficit Hyperactivity Disorder and Tics: Preliminary Clinical Experience. Journal Of The American Academy Of Child & Adolescent Psychiatry 1988, 27: 811-814. PMID: 3198572, DOI: 10.1097/00004583-198811000-00027.Peer-Reviewed Original ResearchConceptsAttention deficit hyperactivity disorderGlobal improvement ratingTourette syndromeTic symptomsDMI treatmentHyperactivity disorderCommon side effectsChronic tic disorderPreliminary clinical experienceSymptoms of ADHDDesipramine treatmentMild tachycardiaImprovement ratingStandard treatmentClinical evaluationTic disordersFamily historyCNS stimulantsSide effectsClinical experiencePatientsMarked reductionRating ScaleDesipramineSymptoms
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