2015
The effects of alcohol-containing e-cigarettes on young adult smokers
Valentine GW, Jatlow PI, Coffman M, Nadim H, Gueorguieva R, Sofuoglu M. The effects of alcohol-containing e-cigarettes on young adult smokers. Drug And Alcohol Dependence 2015, 159: 272-276. PMID: 26778759, PMCID: PMC5171208, DOI: 10.1016/j.drugalcdep.2015.12.011.Peer-Reviewed Original ResearchConceptsSubjective drug effectsE-cigarettesDrug effectsAlcohol metabolitesPlasma alcohol levelsUrine ethyl glucuronideLong-term health risksYoung adult smokersAlcohol conditionE-liquidsAcute safetyAdult smokersNicotine intakeAcute changesSafety dataNicotine addictionCrossover designBiochemical measuresAlcohol levelsPsychomotor performanceElectronic cigarettesDexterity testVulnerable populationsEthyl glucuronideMotor performance
2007
Regionally Specific Regulation of ERK MAP Kinase in a Model of Antidepressant-Sensitive Chronic Depression
Gourley SL, Wu FJ, Kiraly DD, Ploski JE, Kedves AT, Duman RS, Taylor JR. Regionally Specific Regulation of ERK MAP Kinase in a Model of Antidepressant-Sensitive Chronic Depression. Biological Psychiatry 2007, 63: 353-359. PMID: 17889834, PMCID: PMC2277331, DOI: 10.1016/j.biopsych.2007.07.016.Peer-Reviewed Original ResearchMeSH KeywordsAmitriptylineAnimalsAnti-Inflammatory AgentsAntidepressive Agents, TricyclicChronic DiseaseConditioning, OperantCorticosteroneCREB-Binding ProteinDentate GyrusDepressive Disorder, MajorDisease Models, AnimalEndoplasmic Reticulum Chaperone BiPExtracellular Signal-Regulated MAP KinasesFluoxetineHeat-Shock ProteinsHippocampusLocomotionMiceMice, Inbred C57BLMolecular ChaperonesMotivationSelective Serotonin Reuptake InhibitorsConceptsAntidepressant efficacyChronic corticosteroneDentate gyrusChronic depressionCA1/CA3Depression-like behaviorExtracellular signal-regulated kinase 1/2Response element-binding proteinSignal-regulated kinase 1/2Amitriptyline treatmentGlucocorticoid exposureADT treatmentNaive rodentsBehavioral despairLong-term consequencesTail suspensionElement-binding proteinCyclic adenosine monophosphateBiochemical measuresERK MAP kinasePrefrontal cortexHeat shock proteinsOperant conditioning taskCommon mediatorPERK1/2
1996
Quality of Life in Peritoneal Dialysis Patients
STEELE T, BALTIMORE D, FINKELSTEIN S, JUERGENSEN P, KLIGER A, FINKELSTEIN F. Quality of Life in Peritoneal Dialysis Patients. The Journal Of Nervous And Mental Disease 1996, 184: 368-374. PMID: 8642387, DOI: 10.1097/00005053-199606000-00007.Peer-Reviewed Original ResearchConceptsOverall QOLSomatic symptomsEnd-stage renal disease patientsPsychological symptomsContinuous ambulatory peritoneal dialysisPatients' overall QOLPeritoneal dialysis patientsRenal disease patientsAmbulatory peritoneal dialysisAdequacy of dialysisQuality of lifeDialysis patientsPeritoneal dialysisPatient evaluationDisease patientsDialysis adequacyDepressive symptomsPsychological statusBiochemical measuresQoLSymptomsPatientsAnxiety symptomsDialysisSelf-rating form
1995
m-Chlorophenylpiperazine in patients with obsessive-compulsive disorder: Absence of symptom exacerbation
Goodman W, McDougle C, Price L, Barr L, Hills O, Caplik J, Charney D, Heninger G. m-Chlorophenylpiperazine in patients with obsessive-compulsive disorder: Absence of symptom exacerbation. Biological Psychiatry 1995, 38: 138-149. PMID: 7578657, DOI: 10.1016/0006-3223(94)00235-u.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderDrug-free patientsPlasma prolactin responseSeparate test daysOCD symptomsRatings of anxietySymptom exacerbationIntravenous routeProlactin responseOral administrationSusceptible subgroupsBiochemical measuresObsessive-compulsive symptomsSymptomsRandom orderMCPPTest dayPatientsSignificant increaseDisordersBehavioral findingsFindingsPlaceboExacerbationChlorophenylpiperazine
1994
Aspartame, behavior, and cognitive function in children with attention deficit disorder.
Shaywitz B, Sullivan C, Anderson G, Gillespie S, Sullivan B, Shaywitz S. Aspartame, behavior, and cognitive function in children with attention deficit disorder. 1994, 93: 70-5. PMID: 7505423, DOI: 10.1542/peds.93.1.70.Peer-Reviewed Original ResearchConceptsAttention deficit disorderWisconsin Card Sorting TestDeficit disorderTreatment Emergent Symptom ScalePlacebo-controlled crossover studyComplete blood cell countStudy centersLiver function testsUrinary excretion rateBlood cell countAdministration of aspartameMental Disorders criteriaCognitive testsMeasurement of catecholaminesCrossover studyFunction testsMonoamine metabolismInpatient admissionsMetabolite excretionLarge dosesSymptom ScaleUsual consumptionCell countPlasma phenylalanineBiochemical measures
1982
Clonidine suppression of noradrenergic hyperactivity during morphine withdrawal by clonidine: biochemical studies in rodents and primates.
Roth R, Elsworth J, Redmond D. Clonidine suppression of noradrenergic hyperactivity during morphine withdrawal by clonidine: biochemical studies in rodents and primates. The Journal Of Clinical Psychiatry 1982, 43: 42-6. PMID: 6806253.Peer-Reviewed Original ResearchConceptsBrain levelsMHPG accumulationNE turnoverNE neuronsLocus coeruleusNaloxone-insensitive mechanismAdministration of naloxoneMorphine-dependent animalsNE systemDose-dependent degreeNon-human primatesNE metabolismMorphine withdrawalOpiate withdrawalClonidine suppressionImpulse flowNoradrenergic hyperactivityClinical studiesCSF measuresControl monkeysClonidineElectrophysiological studiesMHPGBiochemical measuresPilot data
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