2021
Association of the kynurenine pathway metabolites with clinical, cognitive features and IL-1β levels in patients with schizophrenia spectrum disorder and their siblings
Noyan H, Erdağ E, Tüzün E, Yaylım İ, Küçükhüseyin Ö, Hakan M, Gülöksüz S, Rutten B, Saka M, Atbaşoğlu C, Alptekin K, van Os J, Üçok A. Association of the kynurenine pathway metabolites with clinical, cognitive features and IL-1β levels in patients with schizophrenia spectrum disorder and their siblings. Schizophrenia Research 2021, 229: 27-37. PMID: 33609988, DOI: 10.1016/j.schres.2021.01.014.Peer-Reviewed Original ResearchConceptsSchizophrenia spectrum disordersIL-1β levelsKYNA levelsHigher serum IL-1β levelsSerum IL-1β levelsHigher KYNA levelsTrp-Kyn pathwayKynurenic acid levelsSimilar clinical featuresPathophysiology of schizophreniaManifestations of schizophreniaKYN levelsSerum interleukinClinical featuresInflammatory cytokinesIL-1βClinical dataKynurenine pathwayTRP levelsSpectrum disorderControl groupAdvanced stageLow TrpPathway dysregulationPatients
2013
Celiac Disease in a Child With Ulcerative Colitis
Cheng SX, Raizner A, Phatak UP, Cho JH, Pashankar DS. Celiac Disease in a Child With Ulcerative Colitis. Journal Of Clinical Gastroenterology 2013, 47: 127-129. PMID: 23314669, PMCID: PMC4425271, DOI: 10.1097/mcg.0b013e318250e468.Peer-Reviewed Original ResearchMeSH KeywordsAnti-Inflammatory Agents, Non-SteroidalCeliac DiseaseChildColitis, UlcerativeDiet, Gluten-FreeEndoscopy, GastrointestinalGastrointestinal AgentsGenetic Predisposition to DiseaseGenetic TestingHumansMaleMesalaminePhenotypePredictive Value of TestsProtein Tyrosine Phosphatase, Non-Receptor Type 2Serologic TestsSteroidsTreatment OutcomeConceptsInflammatory bowel diseaseUlcerative colitisCeliac diseaseBowel diseaseGenetic testingDuodenal villous atrophyElevated inflammatory markersGluten-free dietHistory of anemiaSimilar clinical featuresDifferent therapeutic approachesPatient genetic testingCeliac antibodiesMesalamine therapyInflammatory markersVillous atrophyEndoscopic evaluationClinical featuresCrohn's diseaseBloody diarrheaIndividual patientsTherapeutic approachesUnusual caseDiseaseColitis
2000
Squamous Cell Carcinoma Arising in Recurrent Respiratory Papillomatosis with Pulmonary Involvement: Emerging Common Pattern of Clinical Features and Human Papillomavirus Serotype Association
Cook J, Hill D, Humphrey P, Pfeifer J, El-Mofty S. Squamous Cell Carcinoma Arising in Recurrent Respiratory Papillomatosis with Pulmonary Involvement: Emerging Common Pattern of Clinical Features and Human Papillomavirus Serotype Association. Modern Pathology 2000, 13: 914-918. PMID: 10955460, DOI: 10.1038/modpathol.3880164.Peer-Reviewed Original ResearchConceptsRecurrent respiratory papillomatosisSquamous cell carcinomaJuvenile-onset recurrent respiratory papillomatosisRespiratory papillomatosisCell carcinomaClinical featuresInvasive carcinomaHPV-11Malignant transformationFatal squamous cell carcinomaHuman papillomavirus typingHPV 11 DNASimilar clinical featuresYoung adult menPulmonary papillomaPulmonary involvementSquamous papillomaHPV typingBenign papillomasPapillomatosisSerotype associationCarcinomaAdult menPapillomasLung
1987
Severe hypervitaminosis A in siblings: Evidence of variable tolerance to retinol intake
Carpenter T, Pettifor J, Russell R, Pitha J, Mobarhan S, Ossip M, Wainer S, Anast C. Severe hypervitaminosis A in siblings: Evidence of variable tolerance to retinol intake. The Journal Of Pediatrics 1987, 111: 507-512. PMID: 3655980, DOI: 10.1016/s0022-3476(87)80109-9.Peer-Reviewed Original ResearchConceptsSimilar clinical featuresRetinyl ester levelsRetinol intakeTherapeutic trialsClinical featuresHypervitaminosis ADietary vitaminLiver spreadVitamin AMicrograms/Total vitaminInfusionRetinyl estersSame dietIntakeEventual deathVitaminEster levelsYounger brotherAgent 2SyndromeSymptomsYearsExcretionIntoxication
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