1999
Effects of long-term intake of retinol on selected clinical and laboratory indexes
Cartmel B, Moon T, Levine N. Effects of long-term intake of retinol on selected clinical and laboratory indexes. American Journal Of Clinical Nutrition 1999, 69: 937-943. PMID: 10232634, DOI: 10.1093/ajcn/69.5.937.Peer-Reviewed Original ResearchConceptsRetinol intakeAdverse effectsLaboratory indicesVitamin A/dCoronary artery disease riskCancer chemoprevention trialsLong-term ingestionMinimal adverse effectsLong-term intakeSkin cancer chemoprevention trialAlkaline phosphataseMedian followPlacebo groupChemoprevention trialsClinical symptomsRetinol groupChemopreventive agentsCholesterol concentrationsHealthy populationSkin cancerModerate riskDisease riskIntakeFurther studiesSignificant differences
1993
The time trend and age—period—cohort effects on incidence of adenocarcinoma of the stomach in connecticut from 1955–1989
Zheng T, Mayne S, Holford T, Boyle P, Liu W, Chen Y, Mador M, Flannery J. The time trend and age—period—cohort effects on incidence of adenocarcinoma of the stomach in connecticut from 1955–1989. Cancer 1993, 72: 330-340. PMID: 8319166, DOI: 10.1002/1097-0142(19930715)72:2<330::aid-cncr2820720205>3.0.co;2-l.Peer-Reviewed Original ResearchConceptsDistal stomachGastric cardiaObserved time trendsRisk factorsIncidence rateBirth cohortAge-adjusted incidence ratesTime trendsDifferent epidemiologic featuresFuture analytic studiesIncrease of adenocarcinomaConnecticut Tumor RegistryIncidence of adenocarcinomaRisk of adenocarcinomaBirth-cohort phenomenonRegression modelingUnited States populationUnspecified subsiteRetinol intakeHiatal herniaTumor RegistryEpidemiologic featuresAlcohol intakeIncident casesEtiologic factors
1987
Severe hypervitaminosis A in siblings: Evidence of variable tolerance to retinol intake
Carpenter T, Pettifor J, Russell R, Pitha J, Mobarhan S, Ossip M, Wainer S, Anast C. Severe hypervitaminosis A in siblings: Evidence of variable tolerance to retinol intake. The Journal Of Pediatrics 1987, 111: 507-512. PMID: 3655980, DOI: 10.1016/s0022-3476(87)80109-9.Peer-Reviewed Original ResearchConceptsSimilar clinical featuresRetinyl ester levelsRetinol intakeTherapeutic trialsClinical featuresHypervitaminosis ADietary vitaminLiver spreadVitamin AMicrograms/Total vitaminInfusionRetinyl estersSame dietIntakeEventual deathVitaminEster levelsYounger brotherAgent 2SyndromeSymptomsYearsExcretionIntoxication
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