2024
Neuropeptide and serotonin co-transmission sets the activity pattern in the C. elegans egg-laying circuit
Butt A, Van Damme S, Santiago E, Olson A, Beets I, Koelle M. Neuropeptide and serotonin co-transmission sets the activity pattern in the C. elegans egg-laying circuit. Current Biology 2024, 34: 4704-4714.e5. PMID: 39395419, DOI: 10.1016/j.cub.2024.07.064.Peer-Reviewed Original ResearchHermaphrodite-specific neuronsEgg-laying circuitNLP-3Egg layingTiming of egg layingPromote egg layingCaenorhabditis elegansInactive phasePeptide signalsPersistent internal stateNeural circuit functionMolecular experimentsSerotonin receptorsSerotonin SignalingSerotoninMuscle cellsNeurotransmitter serotoninMultiple signalsNeuropeptideNeuropeptide receptorsCo-transmissionEggsNeural circuitsLayingActive phaseThe influence of psilocybin on subconscious and conscious emotional learning
Casanova A, Ort A, Smallridge J, Preller K, Seifritz E, Vollenweider F. The influence of psilocybin on subconscious and conscious emotional learning. IScience 2024, 27: 110034. PMID: 38883812, PMCID: PMC11177198, DOI: 10.1016/j.isci.2024.110034.Peer-Reviewed Original ResearchPsychedelic-Assisted PsychotherapyAgonist psilocybinFearful facesNeutral cuesEmotional cuesPsychiatric disordersSerotonergic psychedelicsSerotonin SignalingExploratory behaviorPsilocybinEmotional learningLearning effectCuesPlacebo groupPlaceboPsychotherapyLearning rateLearningPsychedelicsSerotoninReinforcement learningDisordersTreatment modalitiesBrainTask
2023
Impact of Stress Exposure on Mental and Physical Health across the Life Span: Molecular mechanisms, Neurobiological abnormalities, and Novel Pathways for Intervention
Cattaneo A, Anacker C, Daskalakis N, Riva M. Impact of Stress Exposure on Mental and Physical Health across the Life Span: Molecular mechanisms, Neurobiological abnormalities, and Novel Pathways for Intervention. Psychoneuroendocrinology 2023, 153: 106142. DOI: 10.1016/j.psyneuen.2023.106142.Peer-Reviewed Original ResearchStress exposureEffects of stress exposureImpact of stress exposureSensorimotor gating deficitsChildhood trauma survivorsNegative outcomesPhysical healthEarly life adversityNegative effects of stressExposure to adversityExposure to stressEffects of stressGating deficitsNeurobiological abnormalitiesNeurobiological mechanismsLife stressLife adversityTrauma survivorsSerotonin SignalingAffective behaviorNeurodevelopmental windowBrain functionAt adulthoodPhysical diseaseMouse hippocampus
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