2025
Serum estradiol and progesterone levels at different time points in the menstrual cycle as predictors of outcome in frozen embryo transfer cycles
Yuceturk A, Karaosmanoglu O, Aslan I, Kopuk S, Korun Z, Yazicioglu C, Seli E, Cakiroglu Y, Tiras B. Serum estradiol and progesterone levels at different time points in the menstrual cycle as predictors of outcome in frozen embryo transfer cycles. European Journal Of Obstetrics & Gynecology And Reproductive Biology 2025, 312: 114509. PMID: 40505433, DOI: 10.1016/j.ejogrb.2025.114509.Peer-Reviewed Original ResearchDay of progesterone initiationFrozen embryo transfer cyclesDay of embryo transferPredicting clinical pregnancyEmbryo transfer cyclesSerum estradiolEmbryo transferProgesterone levelsProgesterone initiationClinical pregnancyTransfer cyclesFrozen single blastocyst transferAssociated with higher clinical pregnancy ratesHigher clinical pregnancy ratesTime pointsSingle blastocyst transferSerum estradiol levelsClinical pregnancy rateFrozen embryo transferWomen aged <Prospective cohort studySerum progesterone >Predictors of outcomeBlastocyst transferOral estradiol
2024
Randomized placebo-controlled, double-blind clinical trial of nanoemulsion curcumin in women with aromatase inhibitor-induced arthropathy: an Alliance/NCORP pilot trial
Lustberg M, Fan-Havard P, Wong F, Hill K, Phelps M, Herrera K, Tsai N, Synold T, Feng Y, Kalu C, Sedrak M, Yee L. Randomized placebo-controlled, double-blind clinical trial of nanoemulsion curcumin in women with aromatase inhibitor-induced arthropathy: an Alliance/NCORP pilot trial. Breast Cancer Research And Treatment 2024, 205: 61-73. PMID: 38280052, PMCID: PMC11062803, DOI: 10.1007/s10549-023-07223-4.Peer-Reviewed Original ResearchAI-induced arthralgiaBrief Pain Inventory-Short FormRandomized placebo-controlledPostmenopausal womenPlacebo-ControlledBreast cancerDouble-blind pilot trialDouble-blind clinical trialGrip strengthReduced risk of recurrenceDiscontinuation of treatmentRisk of recurrenceGastrointestinal adverse effectsPilot trialPlasma curcuminInflammation-related conditionsPatient-reported outcome measuresSerum estradiolWell-toleratedEstrone levelsPurposeAromatase inhibitorsTreatment armsRandomized trialsT0-T3Study agents
2020
Treatment of endometriosis-associated pain with linzagolix, an oral gonadotropin-releasing hormone–antagonist: a randomized clinical trial
Donnez J, Taylor HS, Taylor RN, Akin MD, Tatarchuk TF, Wilk K, Gotteland JP, Lecomte V, Bestel E. Treatment of endometriosis-associated pain with linzagolix, an oral gonadotropin-releasing hormone–antagonist: a randomized clinical trial. Fertility And Sterility 2020, 114: 44-55. PMID: 32505383, DOI: 10.1016/j.fertnstert.2020.02.114.Peer-Reviewed Original ResearchConceptsEndometriosis-associated painBone mineral densityNon-menstrual pelvic painPelvic painDose-dependent fashionSerum estradiolOral gonadotropin-releasing hormone antagonistSevere endometriosis-associated painGonadotropin-releasing hormone antagonistOverall pelvic painRates of amenorrheaDose-ranging trialRandomized clinical trialsNumber of respondersPrimary endpointBMD lossTotal hipFemoral neckHormone antagonistClinical centersParallel groupClinical trialsMineral densityLife measuresMAIN OUTCOME
2009
Chemoprevention of Colorectal Neoplasia by Estrogen: Potential Role of Vitamin D Activity
Protiva P, Cross HS, Hopkins ME, Kállay E, Bises G, Dreyhaupt E, Augenlicht L, Lipkin M, Lesser M, Livote E, Holt PR. Chemoprevention of Colorectal Neoplasia by Estrogen: Potential Role of Vitamin D Activity. Cancer Prevention Research 2009, 2: 43-51. PMID: 19139017, DOI: 10.1158/1940-6207.capr-08-0103.Peer-Reviewed Original ResearchMeSH Keywords25-Hydroxyvitamin D3 1-alpha-HydroxylaseChemopreventionColorectal NeoplasmsEstradiolEstrogen Replacement TherapyEstrogensFemaleGene ExpressionGene Expression ProfilingHumansMiddle AgedReceptors, CalcitriolReverse Transcriptase Polymerase Chain ReactionSteroid HydroxylasesVitamin DVitamin D3 24-HydroxylaseConceptsHormone replacement therapyVitamin D activityReplacement therapyPostmenopausal hormone replacement therapyVitamin D receptor pathwayPrimary end pointRectal mucosal biopsiesVitamin D actionExpression of VDRColon cancer incidenceE-cadherinRegulation of VDREstrogen interventionEstrogen-responsive genesPostmenopausal womenPremenopausal levelsVDR pathwayMucosal biopsiesRectal biopsySerum estradiolVitamin DColorectal neoplasiaD activityRectal mucosaCancer incidence
2004
Serum estradiol positively predicts outcomes in patients undergoing in vitro fertilization
Blazar A, Hogan J, Frankfurter D, Hackett R, Keefe D. Serum estradiol positively predicts outcomes in patients undergoing in vitro fertilization. Fertility And Sterility 2004, 81: 1707-1709. PMID: 15193504, DOI: 10.1016/j.fertnstert.2003.10.039.Peer-Reviewed Original Research
1997
Outcome of IVF in DES-Exposed Daughters: Experience in the 90s
Pal L, Shifren J, Isaacson K, Chang Y, Marean M, Leykin L, Toth T. Outcome of IVF in DES-Exposed Daughters: Experience in the 90s. Journal Of Assisted Reproduction And Genetics 1997, 14: 513-517. PMID: 9401869, PMCID: PMC3454843, DOI: 10.1023/a:1021175326230.Peer-Reviewed Original ResearchConceptsMassachusetts General HospitalOngoing pregnancy rateOutcome of IVFIVF cyclesInfertile womenUtero exposurePregnancy rateAcademic IVF programDay 3 levelsOutcome of ARTSelf-reported historyQuality of embryosOvarian hyperstimulationUtero DiethylstilbestrolControl patientsIdiopathic infertilitySerum estradiolImplantation rateInfertile patientsIVF programGeneral HospitalIVF unitEmbryo transferPatientsLow implantation
1996
Relaxin secretion in in vitro fertilization pregnancies
Haning R, Goldsmith L, Seifer D, Wheeler C, Frishman G, Sarmento J, Weiss G. Relaxin secretion in in vitro fertilization pregnancies. American Journal Of Obstetrics And Gynecology 1996, 174: 233-240. PMID: 8572013, DOI: 10.1016/s0002-9378(96)70400-3.Peer-Reviewed Original ResearchConceptsHuman chorionic gonadotropinSecretion of relaxinChorionic gonadotropinCorpora luteaSerum estradiolSerum relaxinFunctional statusHuman chorionic gonadotropin (hCG) injectionOvarian hyperstimulation syndromeSerum of womenSecretion of steroidsSerum relaxin concentrationsFertilization pregnanciesHyperstimulation syndromePremature deliveryMultiple gestationsGonadotropin injectionRelaxin secretionMore injectionsRelaxin concentrationsProgesterone concentrationsMultiple linear regression analysisPregnancyGonadotropinSteroid concentrations
1992
Baseline ovarian cysts do not affect clinical response to controlled ovarian hyperstimulation for in vitro fertilization**Presented at the 47th Annual Meeting of The American Fertility Society, Orlando, Florida, October 21 to 24, 1991.
Penzias A, Jones E, Seifer D, Grifo J, Thatcher S, DeCherney A. Baseline ovarian cysts do not affect clinical response to controlled ovarian hyperstimulation for in vitro fertilization**Presented at the 47th Annual Meeting of The American Fertility Society, Orlando, Florida, October 21 to 24, 1991. Fertility And Sterility 1992, 57: 1017-1021. PMID: 1572468, DOI: 10.1016/s0015-0282(16)55019-5.Peer-Reviewed Original ResearchConceptsBaseline ovarian cystsNumber of folliclesOvarian cystsOvarian hyperstimulationIVF cyclesClinical responseStimulation regimenBaseline E2 levelBaseline serum estradiolCycle cancellation ratePeak serum E2Vitro Fertilization ProgramAmerican Fertility SocietyNumber of oocytesSerum E2Serum estradiolNumber of cystsCycle outcomeE2 levelsCyst sizeFertility SocietySuch cystsCancellation rateYale University SchoolOwn control
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