2024
Impact of concomitant surgical interventions on outcomes of septal myectomy in obstructive hypertrophic cardiomyopathy
Altibi A, Sapru A, Ghanem F, Zhao Y, Alani A, Cigarroa J, Nazer B, Song H, Masri A. Impact of concomitant surgical interventions on outcomes of septal myectomy in obstructive hypertrophic cardiomyopathy. International Journal Of Cardiology 2024, 400: 131790. PMID: 38242508, DOI: 10.1016/j.ijcard.2024.131790.Peer-Reviewed Original ResearchConceptsObstructive hypertrophic cardiomyopathyMitral valve replacementCoronary Artery Bypass GraftingConcomitant surgical interventionIn-Hospital MortalitySeptal myectomyAdverse in-hospital eventsIn-hospital eventsSurgical interventionMV repairValve replacementHypertrophic cardiomyopathyOutcomes of septal myectomyAssociated with increased in-hospital mortalityOutcomes of patientsAortic valve replacementIn-Hospital Adverse EventsAdverse clinical eventsIsolated SMArtery Bypass GraftingIn-Hospital DeathNational Readmission DatabaseSymptomatic patientsMedical therapyAdverse eventsCardiovascular Hospitalizationspost Septal Myectomy For Obstructive Hypertrophic Cardiomyopathy: A 3-year Analysis Of 5,101 Patients
Altibi A, Elman M, Zhao Y, Chehab J, Butzner M, Heitner S, Jacoby D, Sohn R, Masri A. Cardiovascular Hospitalizationspost Septal Myectomy For Obstructive Hypertrophic Cardiomyopathy: A 3-year Analysis Of 5,101 Patients. Journal Of Cardiac Failure 2024, 30: 199-200. DOI: 10.1016/j.cardfail.2023.10.201.Peer-Reviewed Original ResearchObstructive hypertrophic cardiomyopathyIncidence of cardiovascular hospitalizationsSeptal myectomyCardiovascular hospitalizationChronic kidney diseaseChronic obstructive pulmonary diseaseHypertrophic cardiomyopathyPost-SMVentricular arrhythmiasHeart failureCumulative incidence of cardiovascular hospitalizationsFollow-upYears median follow-upMedian Follow-UpAdvanced HF therapiesHealth claims databaseAdvanced heart failureEmergency department visitsPacemaker/implantable cardioverter defibrillatorObstructive pulmonary diseaseHF therapyAtrial fibrillation/flutterCumulative incidenceCardiac arrestMultivariate regression modelCharacteristics And Procedural Complications Of Septal Myectomy For Obstructive Hypertrophic Cardiomyopathy In The United States
Altibi A, Elman M, Zhao Y, Chehab J, Butzner M, Heitner S, Jacoby D, Sohn R, Masri A. Characteristics And Procedural Complications Of Septal Myectomy For Obstructive Hypertrophic Cardiomyopathy In The United States. Journal Of Cardiac Failure 2024, 30: 177-178. DOI: 10.1016/j.cardfail.2023.10.149.Peer-Reviewed Original ResearchObstructive hypertrophic cardiomyopathySeptal myectomyBaseline characteristicsHypertrophic cardiomyopathyInpatient complicationsConcomitant mitral valve repairVentricular septal defectMitral valve repairMitral valve replacementPredictor of inpatient complicationsCohort of patientsOutcomes of SMValve repairSeptal defectValve replacementAtrial fibrillation/flutterAnoxic brain damagePacemaker implantationAdult patientsHeart blockCardiac arrestEmergency intubationProcedural outcomesContinuous enrollmentMyectomy
2023
Hospital Procedural Volume and Clinical Outcomes Following Septal Reduction Therapy in Obstructive Hypertrophic Cardiomyopathy
Altibi A, Ghanem F, Zhao Y, Elman M, Cigarroa J, Nazer B, Song H, Masri A. Hospital Procedural Volume and Clinical Outcomes Following Septal Reduction Therapy in Obstructive Hypertrophic Cardiomyopathy. Journal Of The American Heart Association 2023, 12: e028693. PMID: 37183831, PMCID: PMC10227305, DOI: 10.1161/jaha.122.028693.Peer-Reviewed Original ResearchConceptsAlcohol septal ablationSeptal reduction therapyObstructive hypertrophic cardiomyopathyIn-Hospital MortalitySeptal ablationSeptal myectomyHypertrophic cardiomyopathyReduction therapyVolume-outcome relationshipVolume tertilesInverse volume-outcome relationshipPost-SMProcedure volumeIncidence of in-hospital deathAdverse in-hospital eventsIn-hospital eventsIn-Hospital DeathNational Readmission DatabaseHigh-volume hospitalsHospital procedure volumeAnnual procedure volumeClinical outcomesContemporary outcomesReadmissions DatabaseHospital volumeDiscrepant Volume-cost Relationship Of Septal Reduction Therapies For The Treatment Of Obstructive Hypertrophic Cardiomyopathy
Altibi A, Ghanem F, Masri A. Discrepant Volume-cost Relationship Of Septal Reduction Therapies For The Treatment Of Obstructive Hypertrophic Cardiomyopathy. Journal Of Cardiac Failure 2023, 29: 639-640. DOI: 10.1016/j.cardfail.2022.10.228.Peer-Reviewed Original ResearchAlcohol septal ablationSeptal reduction therapyObstructive hypertrophic cardiomyopathyHigh-volume centersSeptal myectomyTertile of hospital volumeLow-volume centersNational Readmission DatabaseSeptal ablationHypertrophic cardiomyopathyTreatment of obstructive hypertrophic cardiomyopathyReduction therapyAlcohol septal ablation proceduresInverse volume-cost relationshipHospital volumeProcedure volumeHospital procedure volumeMedical therapyAnnual procedure volumeReadmissions DatabaseAverage annual chargesInflation-adjusted chargesVolume-cost relationshipHospital costsTherapy
2021
Predictive value of NT-proBNP in non-obstructive hypertrophic cardiomyopathy
Hutt E, Mentias A, Alashi A, Fava A, Popovic Z, Thamilarasan M, Lever H, Desai M. Predictive value of NT-proBNP in non-obstructive hypertrophic cardiomyopathy. European Heart Journal 2021, 42: ehab724.0765. DOI: 10.1093/eurheartj/ehab724.0765.Peer-Reviewed Original ResearchNT-proBNP ratioLV ejection fractionSerum NT-proBNPNT-proBNPAsymptomatic patientsPrimary endpointSeptal myectomySudden cardiac death risk factorsNon-obstructive hypertrophic cardiomyopathyKaplan-Meier survival analysisDeath risk factorsEarly disease stagesHypertrophic cardiomyopathy patientsImplantable defibrillator dischargesEjection fractionHeart transplantPrimary outcomeRisk stratificationPrognostic valueAdverse outcomesDisease stageCardiomyopathy patientsRisk factorsEcho variablesHypertrophic cardiomyopathy
2018
Surgical management of left ventricular outflow tract obstruction in a specialized hypertrophic obstructive cardiomyopathy center
Hodges K, Rivas CG, Aguilera J, Borden R, Alashi A, Blackstone EH, Desai MY, Smedira NG. Surgical management of left ventricular outflow tract obstruction in a specialized hypertrophic obstructive cardiomyopathy center. Journal Of Thoracic And Cardiovascular Surgery 2018, 157: 2289-2299. PMID: 30782406, DOI: 10.1016/j.jtcvs.2018.11.148.Peer-Reviewed Original ResearchConceptsVentricular outflow tract obstructionOutflow tract obstructionMitral valve interventionLeft ventricular outflow tract obstructionTract obstructionSeptal myectomyValve interventionMitral interventionPostoperative ventricular septal defectContemporary surgical outcomesHypertrophic cardiomyopathy centersPapillary muscle resectionMitral valve replacementPermanent pacemaker insertionComplete heart blockMitral valve pathologyVentricular septal defectHospital outcomesOperative mortalityConcomitant proceduresValve replacementMuscle resectionSingle surgeonHeart blockRetrospective review
2014
Sutureless Aortic Valve Replacement: A Canadian Multicentre Study
Mazine A, Teoh K, Bouhout I, Bhatnagar G, Pelletier M, Voisine P, Demers P, Carrier M, Bouchard D. Sutureless Aortic Valve Replacement: A Canadian Multicentre Study. Canadian Journal Of Cardiology 2014, 31: 63-68. PMID: 25547552, DOI: 10.1016/j.cjca.2014.10.030.Peer-Reviewed Original ResearchConceptsSutureless aortic valve replacementAortic valve replacementParavalvular aortic insufficiencyAortic insufficiencyAlternative to standard aortic valve replacementElderly high-risk surgical patientsStandard aortic valve replacementIsolated aortic valve replacementRisk of permanent pacemaker implantationHigh-risk surgical patientsMultiple valve proceduresPerceval S bioprosthesisPerceval S prosthesisCoronary Artery Bypass GraftingCross-clamp timePermanent pacemaker implantationShorter operative timeCanadian multicenter studyArtery Bypass GraftingIn-Hospital MortalitySeptal myectomyEchocardiographic outcomesPartial sternotomyConcomitant proceduresConsecutive patientsAnomalous Left Coronary Artery in Hypertrophic Cardiomyopathy
Penciu OM, Mojibian H, Sugeng L, Cleman M, Brennan J, DePasquale E, McKenna W, Bonde P, Jacoby D. Anomalous Left Coronary Artery in Hypertrophic Cardiomyopathy. The Annals Of Thoracic Surgery 2014, 97: 2190-2193. PMID: 24882306, DOI: 10.1016/j.athoracsur.2013.07.122.Peer-Reviewed Case Reports and Technical NotesConceptsCoronary arterySignificant left ventricular outflow tract obstructionLeft ventricular outflow tract obstructionVentricular outflow tract obstructionRight ventricular outflow tractSeptal reduction therapyOutflow tract obstructionSingle coronary arteryVentricular outflow tractSudden cardiac deathOpposite sinusAnomalous originTract obstructionRight sinusSeptal myectomyCardiac catheterizationCardiac deathMedical therapyTomography angiogramOutflow tractHypertrophic cardiomyopathyCommon causeReduction therapyImplantable cardioverterArtery
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