2025
Evaluating factors impacting early career physician-scientists’ decisions to continue research careers in the United States of America
Farhat K, Obradovic A, Siebert A, Tun H, Noch E, Kwan J. Evaluating factors impacting early career physician-scientists’ decisions to continue research careers in the United States of America. BMC Medical Education 2025, 25: 564. PMID: 40247298, PMCID: PMC12007356, DOI: 10.1186/s12909-025-07144-4.Peer-Reviewed Original ResearchConceptsPhysician-scientistsTraining programGraduates of training programsEarly-career physician-scientistsFisher's exact testWork-life balanceStages of clinical trainingMaintain work-life balancePhysician-scientist workforcePatient careExact testMethodsA surveyClinical trainingIncomplete responseUnited StatesLack of fundingNational surveyChi-squareCompare differencesSeeking employmentScientific innovationScientific trackResearch careerVulnerable communitiesResearch fundingFour Opportunities To Revitalize The US Biomedical Research Enterprise
Reece E, Balser J, Bibbins-Domingo K, Fraser C, Fried L, Kurth A, Parikh S, Rutta R, Woolley M, Yamamoto K, Zerhouni E, Zoghbi H, Dzau V. Four Opportunities To Revitalize The US Biomedical Research Enterprise. Health Affairs 2025, 44: 140-147. PMID: 39841931, DOI: 10.1377/hlthaff.2024.01001.Peer-Reviewed Original ResearchConceptsNational Academy of Medicine's Vital DirectionsBiomedical research enterpriseReduce health disparitiesHealth equity gapsComplex health issuesNational health outcomesResearch enterpriseFederal research fundingHealth disparitiesResearch fundingWorkforce recruitmentHealth outcomesRetention challengesPromote healthy longevityHealth issuesHealthy longevityVital directionsEquity gapNational Advisory BodyWorkforceNational AcademyPriorityDisparitiesFundingGlobal competitionChapter 34 Federal and foundation funding for gun violence prevention programming and research
Degutis L. Chapter 34 Federal and foundation funding for gun violence prevention programming and research. 2025, 461-464. DOI: 10.1016/b978-0-323-95272-9.00014-0.ChaptersFirearm violenceFirearm-related violenceReduce firearm violenceViolence prevention programsViolenceFirearmMultidisciplinary research agendaFederal agenciesPublic policyPolitical sciencePrevention programsEvidence-based interventionsPrivate sectorFunding limitationsPublic healthEffective prevention strategiesFundingResearch fundingPolicyLawSustainable investmentResearch agendaFederalPrevention strategiesSocietal burdenSex-Based Bias in Industry Payments to Medical Oncologists
Jan I, De B, Kwon Y, Freeman R, Larkin K, Subramanian S, Pandu P, Song A, Young M, Sayan M, Beier M, Ludmir E, Vapiwala N, Haffty B, Mattes M. Sex-Based Bias in Industry Payments to Medical Oncologists. JCO Oncology Advances 2025 DOI: 10.1200/oa-24-00029.Peer-Reviewed Original ResearchMedical oncologistsNational Plan and Provider Enumeration SystemIndustry paymentsCenters for MedicareGeneral paymentsResearch paymentsNational Institutes of Health (NIHPractice locationIndustry research paymentsSex-based differencesSpeaker feesOncologistsNo significant sex differencesEnumeration systemSex-based biasOpen Payments DatabaseNIH RePORTERSex-basedInvestigate potential differencesSignificant sex differencesOncology researchResearch fundingPayments Database
2024
Factors associated with non-publication of clinical trials in cardiovascular medicine: a cross-sectional analysis
Alawajneh M, Aljabai A, Theeb L, Badwan Z, Alnabi A, Theeb H, Altibi A. Factors associated with non-publication of clinical trials in cardiovascular medicine: a cross-sectional analysis. European Heart Journal 2024, 45: ehae666.3639. DOI: 10.1093/eurheartj/ehae666.3639.Peer-Reviewed Original ResearchCross-sectional analysisClinical trialsIntervention typeLogistic regressionCardiovascular medicineNon-randomised trialsOpen-label trialPublication statusMultivariate logistic regressionArea of clinical researchEnrollment sizeNon-publicationCardiovascular clinical trialsCardiovascular-relatedParticipant ageTriple-blindTrial completionDecreased likelihoodRandomised trialsTrial publicationsPredictor factorsFunding sourcesResearch fundingClinical researchEnrollmentCancer research is not correlated with driver gene mutation burdens
Mendiratta G, Liarakos D, Tong M, Ito S, Ke E, Goshua G, Stites E. Cancer research is not correlated with driver gene mutation burdens. Med 2024, 5: 832-838.e4. PMID: 38908369, PMCID: PMC12092095, DOI: 10.1016/j.medj.2024.05.013.Peer-Reviewed Original ResearchCancer patient populationCancer researchCancer research effortsResearch allocation decisionsNational InstitutePatient populationResearch fundingBurdenBurden of mutationsFunding decisionsCancerGenetic driversGene mutation burdenFunding amountFundingGenetic drivers of cancerAllocation decisionsCancer-associated genesEpidemiologyDrivers of cancerMutational burdenBaselineEffortsFactorsBalance of prioritiesScholarly Activity during Neonatal–Perinatal Medicine Fellowship
Dyess N, Myers P, Dammann C, Chess P, Abramson E, Andy C, Weiss P. Scholarly Activity during Neonatal–Perinatal Medicine Fellowship. American Journal Of Perinatology 2024, 42: 075-083. PMID: 38749483, DOI: 10.1055/a-2327-3908.Peer-Reviewed Original ResearchNeonatal-perinatal medicineFellowship program directorsNeonatal-perinatal medicine fellowship programsNeonatal-perinatal medicine fellowshipFellowship programsBarriers to completionLack of adequate expertisePediatric subspecialty programsFellowship trainingResearch curriculumScholarly activityProgram directorsSubspecialty programsActive trainingAdequate expertiseActivation productsOversight CommitteeResearch mentorsFellowshipResearch fundingGrant applicationsTrends in Firearm Injury Prevention Research Funding, Clinical Trials, and Publications in the US, 1985-2022
Lin J, Chang C, McCarthy M, Baker-Butler A, Tong G, Ranney M. Trends in Firearm Injury Prevention Research Funding, Clinical Trials, and Publications in the US, 1985-2022. JAMA Surgery 2024, 159: 461-463. PMID: 38324281, PMCID: PMC10851134, DOI: 10.1001/jamasurg.2023.7461.Peer-Reviewed Original ResearchPublished research on the human health implications of climate change between 2012 and 2021: cross sectional study
Bartlett V, Doernberg H, Mooghali M, Gupta R, Wallach J, Nyhan K, Chen K, Ross J. Published research on the human health implications of climate change between 2012 and 2021: cross sectional study. BMJ Medicine 2024, 3: e000627. PMID: 38352020, PMCID: PMC10862342, DOI: 10.1136/bmjmed-2023-000627.Peer-Reviewed Original ResearchHealth effects of climate changeHealth research fundingRandom sampleHealth effectsCross sectional studyPeer-reviewed researchWeb of ScienceGrey literatureHealth conditionsSectional studyInclusion criteriaRisk populationHealthHealth impactsHealth implicationsGoogle ScholarResearch articlesNational InstituteFunding sourcesPublication characteristicsResearch fundingPublished researchRiskDisproportionate focusPopulation
2021
Eptacog Beta Efficacy in Children and Adolescents with Hemophilia A or B and Inhibitors: Subset Analysis Suggests Improved Caregiver Capacity to Assess Bleeding Episode Resolution with Subject Age
Young G, Pipe S, Hermans C, Carcao M, Castaman G, Davis J, Ducore J, Dunn A, Escobar M, Journeycake J, Khan O, Mahlangu J, Meeks S, Mitha I, Négrier C, Nowak-Göttl U, Recht M, Chrisentery-Singleton T, Stasyshyn O, Vilchevska K, Martinez L, Wang M, Windyga J, Alexander W, Al-Sabbagh A, Bonzo D, Macie C, Mitchell I, Wilkinson T, Shapiro A. Eptacog Beta Efficacy in Children and Adolescents with Hemophilia A or B and Inhibitors: Subset Analysis Suggests Improved Caregiver Capacity to Assess Bleeding Episode Resolution with Subject Age. Blood 2021, 138: 3195. DOI: 10.1182/blood-2021-147434.Peer-Reviewed Original ResearchInitial dosing regimensEntity's Board of DirectorsEptacog betaBleeding episodesPhase 3 trialCSL BehringPediatric age subgroupsConfidence intervalsTreatment successHemophilia AYears subgroupIncreasing subject ageAge subgroupsSubject ageBeta infusionAdvisory CommitteeResearch fundingOregon Health & Science UniversitySuccess proportionTreatment of bleeding episodesControl of bleeding episodesModerate bleeding episodesTreat bleeding episodesNational Hemophilia FoundationOpen-label trialRisks for Hospitalization and Death Among Patients with Blood Disorders from the ASH RC COVID-19 Registry for Hematology
Hicks L, Redd R, Anderson K, Desai P, Dolan B, Goldberg A, Narendra V, Neuberg D, Radhakrishnan V, Sehn L, Sekeres M, Stahl M, Tallman M, Thompson J, Tucker E, Wood W. Risks for Hospitalization and Death Among Patients with Blood Disorders from the ASH RC COVID-19 Registry for Hematology. Blood 2021, 138: 3040. PMCID: PMC8701544, DOI: 10.1182/blood-2021-154283.Peer-Reviewed Original ResearchEntity's Board of DirectorsTypes of hematological malignanciesPlasma cell dyscrasiaHematologic malignanciesCOVID-19 mortalityMultivariate logistic regressionGrand roundsCOVID-19 registryMale sexCancer treatmentIncreased riskMultivariate analysisICU carePre-COVID-19Blood disordersBristol Myers SquibbCOVID-19 infectionImpact of cancer treatmentLogistic regressionAdvisory CommitteeResearch fundingRisk of COVID-19 mortalityIncreased risk of COVID-19 mortalityMedian age categoryOutcomes of COVID-19 infectionEarly Detection of Pancreatic Cancer
Kenner B, Abrams N, Chari S, Field B, Goldberg A, Hoos W, Klimstra D, Rothschild L, Srivastava S, Young M, Go V. Early Detection of Pancreatic Cancer. Pancreas 2021, 50: 916-922. PMID: 34629446, PMCID: PMC8542068, DOI: 10.1097/mpa.0000000000001882.Peer-Reviewed Original ResearchConceptsElectronic health recordsElectronic health record dataHealth recordsElectronic health record data miningEarly detection of pancreatic cancerAI-based modelsArtificial intelligenceDetection of pancreatic cancerEarly detectionData sharing networksPotential of artificial intelligenceNational Cancer InstituteData miningData extractionData modelSharing networksCancer InstitutePancreatic cancerSecondary useKenner Family Research FundResearch fundingNext stepsGroup of panelistsWorkshopCancer
2019
Increasing gender diversity in the STEM research workforce
Greider CW, Sheltzer JM, Cantalupo NC, Copeland WB, Dasgupta N, Hopkins N, Jansen JM, Joshua-Tor L, McDowell GS, Metcalf JL, McLaughlin B, Olivarius A, O'Shea EK, Raymond JL, Ruebain D, Steitz JA, Stillman B, Tilghman SM, Valian V, Villa-Komaroff L, Wong JY. Increasing gender diversity in the STEM research workforce. Science 2019, 366: 692-695. PMID: 31699926, DOI: 10.1126/science.aaz0649.Peer-Reviewed Original ResearchGender-based harassmentGender-specific barriersAdvancement of womenDomestic laborPolicy changesWomen's abilitySystemic barriersCultural factorsUnequal distributionU.S. institutionsGender diversityResearch institutionsFunding agenciesProfessional focusHarassmentUnconscious biasesResearch fundingResearch workforceInstitutionsCareerSTEM disciplinesResearch careerScientific careerGovernanceSuccessful strategy
2017
The Relationship of Joint Range of Motion to Factor Activity in Patients with Hemophilia A and B without Prophylaxis: A Longitudinal Assessment of the CDC-UDC Hemophilia Dataset
Wang M, Recht M, Iyer N, Cooper D, Soucie J. The Relationship of Joint Range of Motion to Factor Activity in Patients with Hemophilia A and B without Prophylaxis: A Longitudinal Assessment of the CDC-UDC Hemophilia Dataset. Blood 2017, 130: 756. DOI: 10.1182/blood.v130.suppl_1.756.756.Peer-Reviewed Original ResearchRange of motionJoint range of motionCenters for Disease Control and PreventionUniversal Data CollectionEntity's Board of DirectorsROM lossRange of motion measurementsRange of motion lossNormal range of motionAdvisory CommitteeResearch fundingHemophilia ATraining care providersDisease Control and PreventionEffect of patient characteristicsControl and PreventionGeneralized linear regressionMeasures linear regressionLongitudinal assessmentHemophilia BJoint bleedsCare providersJoint rangeComprehensive visitLinear regressionChapter 39 Governmental Support of Research
Vermund S, Karim S. Chapter 39 Governmental Support of Research. 2017, 679-705. DOI: 10.1016/b978-0-12-802101-9.00039-9.Peer-Reviewed Original ResearchNational funding agenciesMultilateral partnershipsResearch agenciesMultinational partnershipsGovernment research agenciesFunding termsFiscal dynamicsTypes of grantsFiscal supportGovernmental supportEuropean CommunityGovernment sourcesFunding optionsOpen competitionGovernmental sourcesDisproportionate shareSouth AfricaAgenciesFunding agenciesFunding sourcesRegional Research InstituteUnited StatesResearch fundingPartnershipNations
2016
Linear and Logistic Regression Models of Patient-Reported Outcomes and Patient Characteristics in US Adults with Hemophilia from the Pain, Functional Impairment, and Quality of Life (P-FiQ) Study
Batt K, Recht M, Wang M, Quon D, Boggio L, Kessler C, Buckner T, Neff A, Iyer N, Cooper D, Kempton C. Linear and Logistic Regression Models of Patient-Reported Outcomes and Patient Characteristics in US Adults with Hemophilia from the Pain, Functional Impairment, and Quality of Life (P-FiQ) Study. Blood 2016, 128: 252. DOI: 10.1182/blood.v128.22.252.252.Peer-Reviewed Original ResearchBrief Pain Inventory v2 Short FormLack of college educationInternational Physical Activity QuestionnaireHaemophilia Activities ListEntity's Board of DirectorsPatient-reported outcomesVisual analog scalePatient-reported outcome instrumentsSevere haemophiliaQuality of lifePatient characteristicsPhysical activityCollege educationCSL BehringFunctional impairmentUS adultsOlder ageHistory of joint painMeasure patient-reported outcomesPhysical Activity QuestionnaireGreater physical activityAdvisory CommitteeAdministration of patient-reported outcomesResearch fundingSubject characteristics
2015
The Clinical Associations and Outcomes of Patients Admitted with Acquired Hemophilia; A Review of the 2012 National Inpatient Sample
Shatzel J, Azar S, Gay N, Luo J, Deloughery T, Recht M, Taylor J. The Clinical Associations and Outcomes of Patients Admitted with Acquired Hemophilia; A Review of the 2012 National Inpatient Sample. Blood 2015, 126: 1091. DOI: 10.1182/blood.v126.23.1091.1091.Peer-Reviewed Original ResearchNational Inpatient SampleAcquired hemophiliaHemophilia AInpatient mortalityInpatient SampleInternational Classification of DiseasesResearch fundingClassification of diseasesCritical illnessClinical associationsDiagnosis of cancerTransfusion of packed red blood cellsPacked red cell transfusionCase of acquired hemophiliaTransfusion of blood productsPacked red blood cellsCoagulation factor transfusionInpatient diagnosisLength of stayClinical ModificationRed cell transfusionInternational ClassificationOutcomes of patientsAdmission dataPregnancy association
2012
Green chemistry and green engineering in China: drivers, policies and barriers to innovation
Matus K, Xiao X, Zimmerman J. Green chemistry and green engineering in China: drivers, policies and barriers to innovation. Journal Of Cleaner Production 2012, 32: 193-203. DOI: 10.1016/j.jclepro.2012.03.033.Peer-Reviewed Original ResearchEconomic growthEnergy efficiency policiesHuman capitalEfficiency policiesCleaner production conceptsWorld's largest populationEnvironmental agendaPollution regulationsBureaucratic barriersFinancial barriersSustainable developmentStrict enforcementInnovationPolicyNational attentionSmall baseKey barriersEnvironmental protectionTechnical barriersCircular economyWorkforce trainingGreen chemistryResearch fundingChinaCrucial barrier
2006
What Characterizes Academic Radiology Departments That Secure Large Amounts of External Funding for Research?
Jonisch AI, Kligerman S, Nagy E, Bhargavan M, Forman HP, Sunshine J. What Characterizes Academic Radiology Departments That Secure Large Amounts of External Funding for Research? Academic Radiology 2006, 13: 1513-1516. PMID: 17191360, DOI: 10.1016/j.acra.2006.09.052.Peer-Reviewed Original Research
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