2024
Stiffening of the human proximal pulmonary artery with increasing age
Manning E, Mishall P, Ramachandra A, Hassab A, Lamy J, Peters D, Murphy T, Heerdt P, Singh I, Downie S, Choudhary G, Tellides G, Humphrey J. Stiffening of the human proximal pulmonary artery with increasing age. Physiological Reports 2024, 12: e16090. PMID: 38884325, PMCID: PMC11181131, DOI: 10.14814/phy2.16090.Peer-Reviewed Original ResearchConceptsProximal pulmonary arteriesPulmonary arteryAge-related stiffeningRight ventricular ejection fractionVentricular ejection fractionMean wall thicknessEjection fractionNo significant differenceSystemic circulationLuminal caliberDiffusing capacityArterial stiffeningIncreasing ageSignificant differenceDistensionArteryWall thicknessAdverse effectsWall strainVessel diameterCyclic biaxial strainOrgan donorsAgeMicrostructural remodeling
2009
The Emerging Role of Minimally Invasive Surgical Techniques for the Treatment of Lung Malignancy in the Elderly
Heerdt PM, Park BJ. The Emerging Role of Minimally Invasive Surgical Techniques for the Treatment of Lung Malignancy in the Elderly. Thoracic Surgery Clinics 2009, 19: 345-351. PMID: 20066946, DOI: 10.1016/j.thorsurg.2009.06.006.Peer-Reviewed Original ResearchElderly patientsLung cancerSurgical techniqueRisk/benefit relationshipPreoperative functional statusHealthy elderly patientsInvasive surgical techniquesNeoadjuvant therapyPerioperative morbidityPhysiologic reserveSurgical candidatesLung malignancyPerioperative stressConventional thoracotomyGeriatric patientsOncologic efficacyFunctional statusPopulation agesPatientsEmerging RoleCancerAgeTreatmentNormal processComorbidities