2017
Pre- and postoperative anemia, acute kidney injury, and mortality after coronary artery bypass grafting surgery: a retrospective observational study
Oprea AD, Del Rio JM, Cooter M, Green CL, Karhausen JA, Nailer P, Guinn NR, Podgoreanu MV, Stafford-Smith M, Schroder JN, Fontes ML, Kertai MD. Pre- and postoperative anemia, acute kidney injury, and mortality after coronary artery bypass grafting surgery: a retrospective observational study. Journal Canadien D'anesthésie 2017, 65: 46-59. PMID: 29098634, DOI: 10.1007/s12630-017-0991-0.Peer-Reviewed Original ResearchConceptsAcute kidney injuryPostoperative acute kidney injuryCoronary artery bypassPostoperative anemiaDay of surgerySerum hemoglobin concentrationPreoperative anemiaHemoglobin concentrationArtery bypassCABG surgeryKidney injuryGlobal Outcomes (KDIGO) Clinical Practice GuidelineIncidence of AKIMultivariable Cox proportional hazards analysisSingle large academic medical centerCox proportional hazards analysisPostoperative hemoglobin concentrationPostoperative hemoglobin levelsLong-term mortalityTenth postoperative dayProportional hazards analysisRetrospective observational studyLarge academic medical centerClinical practice guidelinesPotential risk factors
2016
Baseline Pulse Pressure, Acute Kidney Injury, and Mortality After Noncardiac Surgery
Oprea AD, Lombard FW, Liu WW, White WD, Karhausen JA, Li YJ, Miller TE, Aronson S, Gan TJ, Fontes ML, Kertai MD. Baseline Pulse Pressure, Acute Kidney Injury, and Mortality After Noncardiac Surgery. Anesthesia & Analgesia 2016, 123: 1480-1489. PMID: 27607474, DOI: 10.1213/ane.0000000000001557.Peer-Reviewed Original ResearchMeSH KeywordsAcademic Medical CentersAcute Kidney InjuryAdultAgedAged, 80 and overArterial PressureChi-Square DistributionFemaleHumansHypertensionIncidenceLogistic ModelsMaleMiddle AgedMultivariate AnalysisNorth CarolinaOdds RatioRetrospective StudiesRisk AssessmentRisk FactorsSeverity of Illness IndexSurgical Procedures, OperativeTime FactorsTreatment OutcomeConceptsPostoperative acute kidney injuryAcute kidney injuryBaseline pulse pressureNoncardiac surgeryPulse pressureKidney injuryIncidence of AKIAdvanced stageBaseline arterial blood pressureMultivariable logistic regression analysisDuke University Medical CenterPreoperative pulse pressurePerioperative risk factorsArterial blood pressureImportant independent predictorLogistic regression analysisUniversity Medical CenterRisk-adjusted modelsCardiovascular outcomesAdult patientsBlood pressureCardiac surgeryIndependent predictorsRisk factorsMedical CenterRisk stratification, perioperative and periprocedural management of the patient receiving anticoagulant therapy
Oprea AD, Noto CJ, Halaszynski TM. Risk stratification, perioperative and periprocedural management of the patient receiving anticoagulant therapy. Journal Of Clinical Anesthesia 2016, 34: 586-599. PMID: 27687455, DOI: 10.1016/j.jclinane.2016.06.016.Peer-Reviewed Original ResearchConceptsPeriprocedural managementPerioperative periodInterventional pain proceduresRandomized clinical trialsAntithrombotic therapyAnticoagulant therapyPerioperative managementThromboembolic complicationsCoronary diseaseRisk stratificationAtrial fibrillationOutpatient settingPain proceduresClinical trialsRegional anesthesiaClinical judgmentUS populationTherapeutic useTime pointsAnticoagulantsTherapySubsequent increaseSpecial considerationAnticoagulationComplications
2015
Comparison Between the 2007 and 2014 American College of Cardiology/American Heart Association Guidelines on Perioperative Evaluation for Noncardiac Surgery
Oprea AD, Fontes ML, Onaitis MW, Kertai MD. Comparison Between the 2007 and 2014 American College of Cardiology/American Heart Association Guidelines on Perioperative Evaluation for Noncardiac Surgery. Journal Of Cardiothoracic And Vascular Anesthesia 2015, 29: 1639-1650. PMID: 26341877, DOI: 10.1053/j.jvca.2015.04.021.Peer-Reviewed Original Research
2012
Comparison of the Effect on Long-Term Outcomes in Patients With Thoracic Aortic Aneurysms of Taking Versus Not Taking a Statin Drug
Jovin IS, Duggal M, Ebisu K, Paek H, Oprea AD, Tranquilli M, Rizzo J, Memet R, Feldman M, Dziura J, Brandt CA, Elefteriades JA. Comparison of the Effect on Long-Term Outcomes in Patients With Thoracic Aortic Aneurysms of Taking Versus Not Taking a Statin Drug. The American Journal Of Cardiology 2012, 109: 1050-1054. PMID: 22221941, DOI: 10.1016/j.amjcard.2011.11.038.Peer-Reviewed Original ResearchConceptsThoracic aortic aneurysmLong-term outcomesComposite end pointAortic aneurysmAneurysm repairEnd pointImproved long-term outcomesOutcomes of patientsCohort of patientsKaplan-Meier analysisMedian followStatin intakeStatin therapyMedical therapyStatinsFirst presentationPatientsSurvival rateAneurysmsStatin drugsOutcomesTherapyIntakeRepairCohort