2016
Baseline Pulse Pressure, Acute Kidney Injury, and Mortality After Noncardiac Surgery
Oprea AD, Lombard FW, Liu WW, White WD, Karhausen JA, Li YJ, Miller TE, Aronson S, Gan TJ, Fontes ML, Kertai MD. Baseline Pulse Pressure, Acute Kidney Injury, and Mortality After Noncardiac Surgery. Anesthesia & Analgesia 2016, 123: 1480-1489. PMID: 27607474, DOI: 10.1213/ane.0000000000001557.Peer-Reviewed Original ResearchMeSH KeywordsAcademic Medical CentersAcute Kidney InjuryAdultAgedAged, 80 and overArterial PressureChi-Square DistributionFemaleHumansHypertensionIncidenceLogistic ModelsMaleMiddle AgedMultivariate AnalysisNorth CarolinaOdds RatioRetrospective StudiesRisk AssessmentRisk FactorsSeverity of Illness IndexSurgical Procedures, OperativeTime FactorsTreatment OutcomeConceptsPostoperative acute kidney injuryAcute kidney injuryBaseline pulse pressureNoncardiac surgeryPulse pressureKidney injuryIncidence of AKIAdvanced stageBaseline arterial blood pressureMultivariable logistic regression analysisDuke University Medical CenterPreoperative pulse pressurePerioperative risk factorsArterial blood pressureImportant independent predictorLogistic regression analysisUniversity Medical CenterRisk-adjusted modelsCardiovascular outcomesAdult patientsBlood pressureCardiac surgeryIndependent predictorsRisk factorsMedical Center
2015
The influence of clopidogrel on ischemia diagnosed by myocardial perfusion stress testing
Jovin IS, Ebisu KA, Oprea AD, Brandt CA, Natale D, Finta LA, Dziura J, Wackers FJ. The influence of clopidogrel on ischemia diagnosed by myocardial perfusion stress testing. Journal Of Nuclear Cardiology 2015, 23: 773-779. PMID: 26338428, DOI: 10.1007/s12350-015-0268-3.Peer-Reviewed Original ResearchConceptsReversible perfusion defectsOdds ratioPerfusion defectsMyocardial perfusion stress testMyocardial perfusion stress testingStress testStress myocardial perfusion scansMyocardial single photon emissionAdenosine stress testInfluence of clopidogrelLikelihood of ischemiaMyocardial perfusion testingUse of clopidogrelCoronary vascular toneExercise stress testMyocardial perfusion scanMyocardial perfusion imagingSingle photon emissionAdenosine receptor antagonistDiagnosis of ischemiaPerfusion scanPerfusion testingVascular toneReceptor antagonistTomography scan
2013
ADP-Receptor Inhibitors in the Perioperative Period: The Good, the Bad, and the Ugly
Oprea AD, Popescu WM. ADP-Receptor Inhibitors in the Perioperative Period: The Good, the Bad, and the Ugly. Journal Of Cardiothoracic And Vascular Anesthesia 2013, 27: 779-795. PMID: 23648080, DOI: 10.1053/j.jvca.2012.11.014.Peer-Reviewed Original ResearchAdenosineCardiac Surgical ProceduresClopidogrelHemorrhageHumansPerioperative CarePiperazinesPlatelet Aggregation InhibitorsPrasugrel HydrochloridePurinergic P2Y Receptor AntagonistsReceptors, Purinergic P2Receptors, Purinergic P2Y12Surgical Procedures, OperativeThiophenesTicagrelorTiclopidineTreatment Outcome
2012
Comparison of the Effect on Long-Term Outcomes in Patients With Thoracic Aortic Aneurysms of Taking Versus Not Taking a Statin Drug
Jovin IS, Duggal M, Ebisu K, Paek H, Oprea AD, Tranquilli M, Rizzo J, Memet R, Feldman M, Dziura J, Brandt CA, Elefteriades JA. Comparison of the Effect on Long-Term Outcomes in Patients With Thoracic Aortic Aneurysms of Taking Versus Not Taking a Statin Drug. The American Journal Of Cardiology 2012, 109: 1050-1054. PMID: 22221941, DOI: 10.1016/j.amjcard.2011.11.038.Peer-Reviewed Original ResearchConceptsThoracic aortic aneurysmLong-term outcomesComposite end pointAortic aneurysmAneurysm repairEnd pointImproved long-term outcomesOutcomes of patientsCohort of patientsKaplan-Meier analysisMedian followStatin intakeStatin therapyMedical therapyStatinsFirst presentationPatientsSurvival rateAneurysmsStatin drugsOutcomesTherapyIntakeRepairCohort