2019
Contemporary personalized β-blocker management in the perioperative setting
Oprea AD, Wang X, Sickeler R, Kertai MD. Contemporary personalized β-blocker management in the perioperative setting. Journal Of Anesthesia 2019, 34: 115-133. PMID: 31637510, DOI: 10.1007/s00540-019-02691-9.Peer-Reviewed Original ResearchConceptsPerioperative β-blocker useΒ-blocker useMajor postoperative cardiac eventsPost-acute myocardial infarctionCardiac adverse eventsPostoperative cardiac eventsSystolic heart failureBeta-adrenergic blockersLong-term treatmentCase-based reviewAdverse eventsCardiac eventsPerioperative periodPerioperative useCardiac surgeryHeart failureMyocardial infarctionPerioperative settingEarlier small-scale studiesTrialsEvaluation trialsPotential benefitsNoncardiacEarlier findingsInfarction
2016
Baseline Pulse Pressure, Acute Kidney Injury, and Mortality After Noncardiac Surgery
Oprea AD, Lombard FW, Liu WW, White WD, Karhausen JA, Li YJ, Miller TE, Aronson S, Gan TJ, Fontes ML, Kertai MD. Baseline Pulse Pressure, Acute Kidney Injury, and Mortality After Noncardiac Surgery. Anesthesia & Analgesia 2016, 123: 1480-1489. PMID: 27607474, DOI: 10.1213/ane.0000000000001557.Peer-Reviewed Original ResearchMeSH KeywordsAcademic Medical CentersAcute Kidney InjuryAdultAgedAged, 80 and overArterial PressureChi-Square DistributionFemaleHumansHypertensionIncidenceLogistic ModelsMaleMiddle AgedMultivariate AnalysisNorth CarolinaOdds RatioRetrospective StudiesRisk AssessmentRisk FactorsSeverity of Illness IndexSurgical Procedures, OperativeTime FactorsTreatment OutcomeConceptsPostoperative acute kidney injuryAcute kidney injuryBaseline pulse pressureNoncardiac surgeryPulse pressureKidney injuryIncidence of AKIAdvanced stageBaseline arterial blood pressureMultivariable logistic regression analysisDuke University Medical CenterPreoperative pulse pressurePerioperative risk factorsArterial blood pressureImportant independent predictorLogistic regression analysisUniversity Medical CenterRisk-adjusted modelsCardiovascular outcomesAdult patientsBlood pressureCardiac surgeryIndependent predictorsRisk factorsMedical Center