Breast, Phase III
A Phase III Clinical Trial Evaluating De-Escalation of Breast Radiation for Conservative Treatment of Stage I, Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer
Volunteers
Health Professionals
What is the purpose of this trial?
This Phase III Trial evaluates whether breast conservation surgery and endocrine therapy results in a non-inferior rate of invasive or non-invasive ipsilateral breast tumor recurrence (IBTR) compared to breast conservation with breast radiation and endocrine therapy.
- Trial withNRG Oncology
- Ages50 years - 70 years
- GenderBoth
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Principal Investigator
Sub-Investigators
- Adriana Matutino Kahn, MD
- Alice Wnuk
- Allison Campbell, MD, PhD
- Anca Bulgaru, MD
- Andrea Brennan
- Andrea Silber, MD
- Armand Russo, MD
- Benjamin Newton, MD
- Beverly Drucker, MD, PhD
- Bruce A. McGibbon, MD
- Christi Kim, MD, FACP
- D. Barry Boyd, MD, MS
- Daniel O'Neil, MD, MPH
- David Witt, MD
- Elan Gorshein, DO, JD, MPH
- Emily Kopas, APRN, OCN
- Eric Winer, MD
- Gineesha Abraham
- Ian Krop, MD, PhD
- James Laird, MD
- Jane Kanowitz, MD
- Jason Haldas, MD
- Jeremy Kortmansky, MD
- Johanna LaSala, MD
- Justin Persico, MD
- Kathleen Fenn, MD
- Kathryn Mason
- Kevin Du, MD, PhD, MSCI
- Kristen Hoxie
- Lajos Pusztai, MD, DPhil
- Larisa Fleysher
- Laura J. Morrison, MD, FAAHPM, FACP
- Lynn D. Wilson, MD, MPH, FASTRO
- M. Sung Lee, MD
- Mariya Rozenblit, MD
- Maryam Lustberg, MD, MPH
- Matthew Austin, MD
- Meena S. Moran, MD
- Michael Cohenuram, MD
- Michael DiGiovanna, MD, PhD
- Michelle Corso
- Neal Fischbach, MD
- Rebecca Vanasse-Passas, MD
- Renee Moye
- Robert Legare, MD
- Sara Anastasio, RN
- Sarah Carlson
- Sarah Elizabeth Schellhorn, MD
- Shari Damast, MD
- Stephen Lattanzi, MD
- Su Hsien Lim, MD
- Susan A. Higgins, MD
- Suzanne B. Evans, MD, MPH, FASTRO
- Tara Sanft, MD
- Vanna Dest
- Virginia Syombathy
- Wajih Kidwai, MD, FACP
- Last Updated04/19/2024
- Study HIC#2000033838