YCCI News

The FDA Office of Minority Health and Health Equity awarded the Yale School of Medicine a $3 million contract to promote diversity in clinical trials.

Pooled testing allows labs to combine saliva samples from multiple individuals into a single tube and process the batch as a single test. This approach maintains clinical sensitivity while enabling labs to process tests far more quickly.

The vaccine will be under an emergency use authorization (EUA), which is granted to products during public health emergencies.

Yale made great strides in this area at the height of the COVID-19 pandemic, and the work now being funded will build on that work by further refining approaches to building trust and participation in clinical trials in diverse communities across the country.

Motor dysfunction often leads to a diagnosis of Parkinson’s disease, but around 80% of patients also develop debilitating cognitive impairments that profoundly impact them and their families. With the support of the ASAP grant, the researchers hope to better understand brain connectivity changes that underlie these cognitive impairments.

New preliminary guidelines suggest that adults who may be prone to cardiovascular disease may benefit more from blood pressure management or statins than aspirin.

Two Yale-led studies suggest that a standard measurement designed to help predict which patients have the best chances of survival—and who therefore should receive treatment—could promote racial disparities of treatment outcomes.

Black girls make up a relatively small portion of the overall drug-using population. But their health consequences are more severe than most: Reproductive issues, fertility issues, sexually transmitted infections and trauma exposure are all obstacles they face at statistically higher rates compared to their peers.

Dr. Samit Shah is leading a team to demonstrate the effectiveness of validated, but not widely administered procedures for the many women who have reduced blood flow to the heart without blocked arteries or cholesterol build-up often associated with heart disease.