YCCI News

Yale researchers reveal the effects of fatty acids on astrocyte function and how they are mediated by diet. These insights, they say, could help identify a potential target for treating obesity and Type 2 diabetes.

Akiko Iwasaki and her colleagues found that intranasal vaccination provided broad-based protection against heterologous respiratory viruses in mice, while so-called systemic immunization, which uses an injection to elicit body-wide protection, did not.

Mutations of a gene that regulates formation of blood vessels in the brain of vertebrates can lead to potentially deadly aneurysms in adults, Yale School of Medicine researchers report in the December issue of Nature Medicine.

Treatment of peripheral artery disease is critical—if left unmanaged, reduced blood flow to the foot can result in serious consequences such as non-healing wounds or even limb loss.

In the past decade, immunotherapy has helped save the lives of many cancer patients, many with lung cancer, who might have otherwise faced almost certain death sentences. However, only about 20% of patients who received immune therapies — designed to enhance or override natural limitations on immune system response — saw sustained benefits from treatment

Arya Mani MD, and colleagues have discovered a therapeutic target for the treatment of nonalcoholic fatty liver disease and liver insulin resistance in type 2 diabetes.

Yale study findings that stress does indeed make life’s clock tick faster — but that individuals can help manage the effects by strengthening their emotion regulation and self-control.

Breakthrough SARS-CoV-2 infections tend to be mild, but new Yale research shows that more older adults have developed severe breakthrough cases during the Delta variant phase of the pandemic, particularly after a longer period of time had elapsed since their last vaccination.

For the first time, there is a potential targeted treatment for kidney injury caused by cisplatin, a widely used anti-cancer drug.