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Addictive Behaviors, Phase Pilot

Imaging Synaptic Density in Cocaine and Opiate Addiction In Vivo using 11C-UCB-J PET

What is the purpose of this trial?

Looking for individuals between 21 and 55 years old currently abusing opiates and not taking medication for it (i.e., Methadone or Buprenorphine). This research study is designed to explore how opiate addiction influences synaptic density. This relationship will be explored in the brain’s prefrontal cortex, an area important in decision-making and impulsivity. In this study, subjects will participate in one 11C-UCB-J Positron Emission Tomography (PET) scan and one structural and functional resting state Magnetic Resonance Imaging (MRI) scan.

This is an inpatient study up to 4 weeks that requires managed abstinence.

Contact Information

For more information about this study, including how to volunteer, contact CNRU Study Team

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You can help our team find trials you might be eligible for by creating a volunteer profile in MyChart. To get started, create a volunteer profile, or contact helpusdiscover@yale.edu, or call 877.978.8343 for more information.

  • Last Updated
    08/02/2024
  • Study HIC
    #2000021843