Clinical Trial Builds Upon Yale Studies to Provide Proof-of-Concept that Subtype-specific Sodium Channel Blockers can Reduce Pain in Humans
Pain is a pervasive symptom encountered by physicians worldwide and a longstanding medical challenge, particularly against the backdrop of the opioid crisis.
Women With Endometriosis Also Genetically Predisposed to Depression, Anxiety, and Eating Disorders
The largest epidemiological study to date on the psychiatric factors that can accompany endometriosis has demonstrated that depression, anxiety, and eating disorders are not only a result of the chronic pain endometriosis generates, but also have their own underlying genetic mechanisms.
Long term Structural and Functional Neural Changes Following a Single Infusion of Ketamine in PTSD
Or Duek, PhD, assistant professor adjunct of psychiatry, and Ilan Harpaz-Rotem, PhD, professor of psychiatry and of psychology, are first and senior authors, respectively of a study published in Neuropsychopharmacology that tests the potential of a single infusion of ketamine, followed by brief exposure therapy, to enhance post-retrieval extinction of post-traumatic stress disorder trauma memories.Source: Neuropsychopharmacology
Diminished Brain Response to Nutrients Observed in People With Obesity
In a new study led by Mireille Serlie, MD, PhD, professor of medicine (endocrinology), researchers found that while the detection of nutrients in the stomach does induce brain activity changes in lean people, such brain responses are largely diminished in people with obesity.Source: Yale News
Yale Researcher Awarded $40 Million to Lead New VA Study to Evaluate Esketamine for Treatment Resistant Depression
Somaia Mohamed, MD, PhD, associate professor of psychiatry, is lead co-investigator of a Department of Veterans Affairs (VA) study that has been awarded $40 million to evaluate the effectiveness of a novel antidepressant medicine, esketamine, for veterans and others with treatment resistant depression (TRD).
Data Sharing That Safeguards Patient Privacy Is Crucial for Future of Medicine, Says Yale Researcher
Sharing patient data for meaningful research presents a significant challenge: protecting patient privacy. Because of advances in computer technology, the theoretical risk of reidentification of anonymous data is very high. Dr. Daniel Boffa is advocating ways to reduce that risk.