Matthew Vesely, MD, PhD
Cards
About
Titles
Assistant Professor of Dermatology
Biography
I am a physician-scientist who has trained in immunology, molecular biology, genetics and clinical dermatology. My overall career goal as a physician-scientist are to integrate fundamental immunology with clinical dermatology. In particular, I am interested in the role of costimulatory and inhibitory immune receptors in cancer immunity, autoimmunity pathogenesis and immunotherapy. My interest in this field was driven by my experience in the Medical Scientist Training Program at Washington University in St. Louis, where I worked in the laboratory of Dr. Robert Schreiber to decipher key molecular regulators of cancer immunoediting. As a consequence, the expertise gained in skin immunology and the emerging immunotherapies to treat melanoma inspired me to become a dermatologist. During my dermatology residency, I joined the laboratory of Dr. Lieping Chen at Yale School of Medicine, who pioneered targeting the PD-1 axis for cancer immunotherapy and has discovered multiple novel immune checkpoint molecules including programmed death receptor-1 homolog (PD-1H) (also known as VISTA). My current research interests include: 1) identification of novel immune checkpoints such as PD-1H/VISTA and others in cutaneous malignancies (e.g., melanoma and keratinocyte carcinomas) and 2) elucidating the inhibitory immune landscape of chronic inflammatory disorders such as psoriasis and cutaneous lupus erythematosus.
Appointments
Dermatology
Assistant ProfessorPrimary
Other Departments & Organizations
- Chen Lab
- Dermatology
- Janeway Society
- Psoriasis Treatment Program
- Vesely Lab
- Yale Medicine
Education & Training
- Resident
- Yale School of Medicine (Dermatology) (2014-2017) (2017)
- Intern
- Barnes Jewish Hospital (St. Louis) (2013-2014) (2014)
- PhD
- Washington University School of Medicine, St. Louis, Immunology (2013)
- MD
- Washington University School of Medicine (2013)
- BS
- Creighton University, Biology, Theology, History (2003)
Research
Overview
Medical Subject Headings (MeSH)
Academic Achievements and Community Involvement
Clinical Care
Overview
Matthew Vesely, MD, is a dermatologist who treats psoriasis, eczema, and other autoimmune skin disorders. Dr. Vesely also sees patients with chronic skin diseases, including discoid lupus erythematosus (DLE) and hidradenitis suppurativa (HS).
“Seeing patients who have been suffering from inflammatory skin diseases for years finally get relief with the help of a targeted therapy is very rewarding,” he says.
Dr. Vesely says he enjoys working with patients and their families to find the best approach to treat a skin disorder. “I always explain that even if the first set of therapies are ineffective, we won't stop until we find the most effective treatment plan,” he says.
Dr. Vesely says he chose his specialty after learning that a large number of skin diseases caused by an overactive immune system lack FDA-approved treatments. In his research, Dr. Vesely investigates emerging new therapies that could potentially help his patients.
“Being able to research the same diseases I treat is extremely gratifying and motivating,” Dr. Vesely says.
Clinical Specialties
Fact Sheets
Prurigo Nodularis
Learn More on Yale MedicineCutaneous T-cell Lymphoma
Learn More on Yale MedicineSeborrheic Keratosis
Learn More on Yale MedicineRosacea
Learn More on Yale Medicine
Board Certifications
Dermatology
- Certification Organization
- AB of Dermatology
- Original Certification Date
- 2017
Yale Medicine News
Links & Media
Media
PD-1H (VISTA) expressed in human cutaneous lupus
PD-1H (VISTA) expression (green) is more abundant in human cutaneous lupus (right) than normal skin (left) and co-localizes with CD3 T cells (red).
Get In Touch
Contacts
Dermatology
333 Cedar Street, LMP 5040, PO Box 208059
New Haven, CT 06520-8059
United States
Locations
Dermatology
Academic Office
Chen Lab
Lab
Patient Care Locations
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Events
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