Yale, Kenyan scientists renew collaboration on tsetse fly research
President Salovey and Serap Aksoy, professor of epidemiology at the Yale School of Public Health, took part in a signing ceremony with the Kenya Agricultural Research and Livestock Organization and Kenyan Wildlife Service to continue an existing collaboration in the biomedical sciences in the area of vector biology.
The enemy within: Gut bacteria drive autoimmune disease
Bacteria found in the small intestines of mice and humans can travel to other organs and trigger an autoimmune response, according to a new Yale study. The researchers also found that the autoimmune reaction can be suppressed with an antibiotic or vaccine designed to target the bacteria, they said.
Zika-related nerve damage caused by immune response to the virus
The immune system’s response to the Zika virus, rather than the virus itself, may be responsible for nerve-related complications of infection, according to a Yale study. This insight could lead to new ways of treating patients with Zika-related complications, such as Guillain-Barré syndrome, the researchers said.
Yale scientists identify key defect in brain tumor cells
In a new study, Yale Cancer Center researchers identified a novel genetic defect that prevents brain tumor cells from repairing damaged DNA. They found that the defect is highly sensitive to an existing FDA-approved drug used to treat ovarian cancer — a discovery that challenges current practice for treatment of brain tumors and other cancers with the same genetic defect, said the scientists.
How Much Can Women Trust That Breast Cancer Biopsy?
When a woman is diagnosed with breast cancer, the person who does the diagnosing is a doctor she never sees — the pathologist. But though pathologists do a great job of identifying invasive cancer, they aren't as good at spotting two less clear-cut diagnoses that bring women a lot of uncertainty and worry, a study finds.Source: NPR
Yale researchers find first cases of new UK coronavirus variant in Connecticut
Gov. Ned Lamont on Jan. 7 announced that Yale researchers in collaboration with the Connecticut Department of Public Health (DPH) detected the first two cases of the SARS-CoV-2 variant B.1.1.7 in the state. This is the same variant initially discovered in the United Kingdom that is associated with increased transmission.Source: Yale News
Chen Liu, MD, PhD, Is Named Chair of Pathology
Chen Liu, MD, PhD, has been chosen to be the next chair of the Department of Pathology at Yale School of Medicine and chief of Pathology at Yale New Haven Hospital, effective March 1, 2020. He comes from Rutgers Biomedical and Health Sciences in New Jersey.
Researchers Identify Stem Cell Source of Key Process in Female Reproduction
Each month during women’s reproductive years, the uterus sheds and regenerates the tissue lining its walls in preparation for a pregnancy or the next cycle. The process behind this age-old and essential part of human reproduction is not well understood. But recent research led by Yale pathologist Wang Min identifies stem cells and a gene that contribute to this monthly event.
Study explores new strategy to develop a malaria vaccine
A serum developed by Yale researchers reduces infection from malaria in mice, according to a new study. It works by attacking a protein in the saliva of the mosquitos infected with the malaria parasite rather than the parasite itself. If the novel approach proves effective in further studies, it could potentially be used to enhance existing malaria vaccines, the researchers said.
Researchers develop a novel RNA-based therapy to target West Nile Virus
A Yale-led research team developed a new RNA therapy, delivered through the nose, to treat mice infected with West Nile Virus. The innovative approach reduced the virus in the brain, allowing the immune system to destroy the virus and develop long-term protection against West Nile Virus disease, the researchers said.