2017
Altered functional connectivity to stressful stimuli in prenatally cocaine-exposed adolescents
Zakiniaeiz Y, Yip SW, Balodis IM, Lacadie CM, Scheinost D, Constable RT, Mayes LC, Sinha R, Potenza MN. Altered functional connectivity to stressful stimuli in prenatally cocaine-exposed adolescents. Drug And Alcohol Dependence 2017, 180: 129-136. PMID: 28888152, PMCID: PMC5808433, DOI: 10.1016/j.drugalcdep.2017.07.030.Peer-Reviewed Original ResearchConceptsPrenatal cocaine exposureNeutral-relaxing conditionsPCE adolescentsParietal connectivityConnectivity analysisSensory areasAdolescent brain functionFunctional magnetic resonance imagingCue interaction effectsIntrinsic connectivity analysesMedial prefrontal areasSeed-based connectivity analysisSubstance Use InitiationAltered functional connectivityAppetitive cuesObesity vulnerabilityPCE statusNeural responsesCorticolimbic connectivityPrefrontal areasFunctional connectivityCraving scoresUtero drug exposureGroup differencesLess connectivity
2013
A preliminary investigation of Stroop-related intrinsic connectivity in cocaine dependence: associations with treatment outcomes
Mitchell MR, Balodis IM, DeVito EE, Lacadie CM, Yeston J, Scheinost D, Constable RT, Carroll KM, Potenza MN. A preliminary investigation of Stroop-related intrinsic connectivity in cocaine dependence: associations with treatment outcomes. The American Journal Of Drug And Alcohol Abuse 2013, 39: 392-402. PMID: 24200209, PMCID: PMC3827911, DOI: 10.3109/00952990.2013.841711.Peer-Reviewed Original ResearchConceptsTreatment outcomesComparison subjectsCocaine-dependent patientsIntrinsic connectivityCocaine dependenceSubstantia nigraVentral striatumTreatment-seeking cocaine-dependent patientsHealthy comparison subjectsPotential treatment targetGreater intrinsic connectivityRegional brain activationCocaine-dependent groupIntrinsic connectivity analysesNon-addicted individualsBasal gangliaInferior frontal gyrusCocaine-dependent individualsTreatment targetsFMRI Stroop taskSubcortical regionsCocaine abstinenceBrain regionsAnterior insulaFrontal gyrus