2024
Overvaluation of shape/weight at posttreatment predicts relapse at 12‐month follow‐up after successful behaviorally‐based treatment of binge‐eating disorder
Grilo C, Ivezaj V, Gueorguieva R. Overvaluation of shape/weight at posttreatment predicts relapse at 12‐month follow‐up after successful behaviorally‐based treatment of binge‐eating disorder. International Journal Of Eating Disorders 2024, 57: 1268-1273. PMID: 38321617, PMCID: PMC11093697, DOI: 10.1002/eat.24141.Peer-Reviewed Original ResearchOvervaluation of shape/weightEating-disorder psychopathologyBinge-eating disorderEating Disorder Examination interviewBeck Depression InventoryWeight loss treatmentClinical overvaluationBinge-eating frequencyDiagnostic specifierBinge eatingNon-abstinenceExamination interviewDepression InventoryShape/weightDepression scoresFollow-upPsychopathologyAbstinenceBingeDepressionClinical implicationsDepression 1PosttreatmentDisordersOvervaluationThe children of parents who receive treatment for binge‐eating disorder experience improvements in disordered eating
Lydecker J, Ozbardakci E, Grilo C. The children of parents who receive treatment for binge‐eating disorder experience improvements in disordered eating. International Journal Of Eating Disorders 2024, 57: 745-751. PMID: 38308384, PMCID: PMC10947894, DOI: 10.1002/eat.24153.Peer-Reviewed Original ResearchBinge-eating disorderBinge eatingDisordered eating behaviorsEating behaviorsSecretive eatingParent changesDisordered eatingAssociated with disordered eating behaviorsEating-disorder psychopathologyEnd-of-treatment assessmentParental eating disordersAssociated with changesChildren of parentsCross-sectional workChild disordered eating behaviorsBinge-eating frequencyEating disordersSchool-aged childrenParental treatmentUntreated family membersParent medicationLongitudinal researchBingeBaseline assessmentEating
2023
Naltrexone/bupropion for binge‐eating disorder: A randomized, double‐blind, placebo‐controlled trial
Grilo C, Lydecker J, Jastreboff A, Pittman B, McKee S. Naltrexone/bupropion for binge‐eating disorder: A randomized, double‐blind, placebo‐controlled trial. Obesity 2023, 31: 2762-2773. PMID: 37751990, PMCID: PMC10600891, DOI: 10.1002/oby.23898.Peer-Reviewed Original ResearchConceptsNaltrexone/bupropionBinge-eating disorderObesity statusLogistic regressionWeight lossPlacebo-controlled trialWeight loss outcomesPrevalent psychiatric disordersEvidence-based treatmentsPost-treatment assessmentBinge-eating frequencyGreater percentage weight lossMedication outcomesRemission ratePharmacological optionsPlaceboBupropionPsychiatric disordersPercentage weight lossMixed modelsDisordersObesityPatientsSignificant reductionWeight reductionNaltrexone plus bupropion combination medication maintenance treatment for binge-eating disorder following successful acute treatments: randomized double-blind placebo-controlled trial
Grilo C, Lydecker J, Gueorguieva R. Naltrexone plus bupropion combination medication maintenance treatment for binge-eating disorder following successful acute treatments: randomized double-blind placebo-controlled trial. Psychological Medicine 2023, 53: 7775-7784. PMID: 37366017, PMCID: PMC10751383, DOI: 10.1017/s0033291723001800.Peer-Reviewed Original ResearchConceptsNaltrexone/bupropionBinge-eating disorderBinge-eating remissionAcute treatmentMaintenance treatmentBinge-eating frequencyDouble-blind placebo-controlled trialBehavioral weight loss therapyWeight lossCo-occurring obesitySuccessful acute treatmentPlacebo-controlled trialWeight loss therapySignificant additional weight lossSingle-site trialAdditional weight lossAcute efficacyRemission rateAdult patientsComorbid obesityBupropionInitial interventionPosttreatment assessmentRespondersPlaceboCognitive‐behavioral therapy for binge‐eating disorder for non‐responders to initial acute treatments: Randomized controlled trial
Grilo C, Lydecker J, Gueorguieva R. Cognitive‐behavioral therapy for binge‐eating disorder for non‐responders to initial acute treatments: Randomized controlled trial. International Journal Of Eating Disorders 2023, 56: 1544-1553. PMID: 37144325, PMCID: PMC10524840, DOI: 10.1002/eat.23975.Peer-Reviewed Original ResearchConceptsInitial acute treatmentBinge-eating disorderCognitive behavioral therapyAcute treatmentBinge-eating frequencyInitial interventionTherapist-led cognitive behavioural therapyInitial pharmacological treatmentTreat remission ratesEvidence-based treatmentsSingle-site trialAcute efficacyRemission rateAdult patientsInitial treatmentPharmacological treatmentPatientsPosttreatment assessmentBehavioral treatmentSufficient benefitTherapyDisordersInterventionTreatmentPharmacotherapy
2018
Comparing men and women with binge‐eating disorder and co‐morbid obesity
Lydecker JA, Grilo CM. Comparing men and women with binge‐eating disorder and co‐morbid obesity. International Journal Of Eating Disorders 2018, 51: 411-417. PMID: 29493793, PMCID: PMC5980708, DOI: 10.1002/eat.22847.Peer-Reviewed Original ResearchConceptsBody mass indexBinge-eating disorderEating-disorder psychopathologyBinge-eating episodesBinge-eating behaviorClinical presentationResearch cliniciansHigher body mass indexCo-morbid obesityDSM-IV disordersStructured Clinical InterviewEating Disorder Examination interviewAge of onsetBinge-eating frequencyRace/ethnicityMass indexBED diagnosisClinical InterviewYounger ageObesityExamination interviewWomenMenAgeDisorders
2017
Form and Formulation: Examining the Distinctiveness of Body Image Constructs in Treatment-Seeking Patients With Binge-Eating Disorder
Lydecker JA, White MA, Grilo CM. Form and Formulation: Examining the Distinctiveness of Body Image Constructs in Treatment-Seeking Patients With Binge-Eating Disorder. Journal Of Consulting And Clinical Psychology 2017, 85: 1095-1103. PMID: 29083224, PMCID: PMC5679782, DOI: 10.1037/ccp0000258.Peer-Reviewed Original ResearchConceptsBody image variablesBody image disturbanceBody image constructsBinge-eating disorderImage constructImage variablesWeight/shape overvaluationBinge-eating frequencyInvestigator-based interviewBiopsychosocial featuresEating-disorder psychopathologyTreatment-seeking patientsShape preoccupationShape dissatisfactionShape overvaluationShape concernsCore aspectsCurrent studyTreatment formulationConstructsImportant distinctionDifferent aspectsOvervaluationPreoccupationDisorders
2016
Binge-eating disorder and major depressive disorder co-morbidity: Sequence and clinical significance
Grilo C, Becker D. Binge-eating disorder and major depressive disorder co-morbidity: Sequence and clinical significance. European Psychiatry 2016, 33: s163. DOI: 10.1016/j.eurpsy.2016.01.322.Peer-Reviewed Original ResearchOnset of MDDOnset of BEDMajor depressive disorderEating-disorder psychopathologyPsychiatric comorbidityDepressive disorderDSM-IV-TR research criteriaEarly onsetCo-occurring major depressive disorderLifetime psychiatric disordersED psychopathologyCo-occurring disordersBinge-eating disorderMeaningful adverse effectsBinge-eating frequencyElevated ratesOrder of onsetTreatment-seeking patientsConsecutive seriesClinical significanceBED patientsPsychiatric disordersMDD groupDiagnostic comorbidityComorbidities
2015
Evaluation of the DSM-5 severity indicator for binge eating disorder in a community sample
Grilo CM, Ivezaj V, White MA. Evaluation of the DSM-5 severity indicator for binge eating disorder in a community sample. Behaviour Research And Therapy 2015, 66: 72-76. PMID: 25701802, PMCID: PMC4346502, DOI: 10.1016/j.brat.2015.01.004.Peer-Reviewed Original ResearchConceptsBinge-eating disorderGreater eating-disorder psychopathologyEating-disorder psychopathologyBinge-eating frequencyModerate severity groupSeverity groupsSeverity criteriaShape/weightDSM-5 severity indicatorDSM-5 severity levelsDSM-5 severity specifiersSeverity specifiersSeverity/frequencyCommunity sampleTreatment-seeking patientsNon-clinical community sample
2014
Comparing weight gain in the year prior to treatment for overweight and obese patients with and without binge eating disorder in primary care
Ivezaj V, Kalebjian R, Grilo CM, Barnes RD. Comparing weight gain in the year prior to treatment for overweight and obese patients with and without binge eating disorder in primary care. Journal Of Psychosomatic Research 2014, 77: 151-154. PMID: 25077857, PMCID: PMC4118055, DOI: 10.1016/j.jpsychores.2014.05.006.Peer-Reviewed Original ResearchConceptsObese patientsBED patientsBinge-eating frequencyWeight gainPrimary careWeight changeCurrent weightGreater eating-disorder psychopathologyNBO patientsWeight change trajectoriesPrimary care physiciansWeight loss treatmentBeck Depression Inventory-IIFurther weight gainEating-disorder psychopathologyRapid weight gainEating Disorder ExaminationCare physiciansWeight historySelf-report questionnairesOverall groupDepression scoresIndependent significant contributionPatientsOverweightTreatment of binge eating disorder in racially and ethnically diverse obese patients in primary care: Randomized placebo-controlled clinical trial of self-help and medication
Grilo CM, Masheb RM, White MA, Gueorguieva R, Barnes RD, Walsh BT, McKenzie KC, Genao I, Garcia R. Treatment of binge eating disorder in racially and ethnically diverse obese patients in primary care: Randomized placebo-controlled clinical trial of self-help and medication. Behaviour Research And Therapy 2014, 58: 1-9. PMID: 24857821, PMCID: PMC4074556, DOI: 10.1016/j.brat.2014.04.002.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAnti-Obesity AgentsBinge-Eating DisorderBlack or African AmericanBody WeightCognitive Behavioral TherapyCombined Modality TherapyCyclobutanesDouble-Blind MethodFemaleHispanic or LatinoHumansMaleMiddle AgedObesityPrimary Health CareSelf CareTime FactorsTreatment OutcomeWhite PeopleYoung AdultConceptsSelf-help cognitive behavioral therapyDiverse obese patientsAnti-obesity medicationsObese patientsModerate clinical outcomePercent weight lossTime interaction effectsWeight lossClinical outcomesPrimary careRandomized placebo-controlled clinical trialSecond placebo-controlled trialPlacebo-controlled clinical trialAcute weight lossPlacebo-controlled trialDouble-blind fashionDiscontinuation of medicationPrimary care settingWeight loss maintenanceSpecialist treatment centresTreatment of bingeDiverse patient groupsSelf-help CBTBinge-eating frequencyDemographic factorsOvervaluation of shape and weight as a mediator between self-esteem and weight bias internalization among patients with binge eating disorder
Pearl RL, White MA, Grilo CM. Overvaluation of shape and weight as a mediator between self-esteem and weight bias internalization among patients with binge eating disorder. Eating Behaviors 2014, 15: 259-261. PMID: 24854815, PMCID: PMC4053161, DOI: 10.1016/j.eatbeh.2014.03.005.Peer-Reviewed Original ResearchConceptsOvervaluation of shapeWeight bias internalizationWeight Bias Internalization ScaleRosenberg Self-Esteem ScaleBinge-eating frequencyWeight biasMediation analysisShape/weightTreatment-seeking individualsSelf-Esteem ScaleInternalization ScaleSemi-structured interviewsBingeOvervaluationClinical effortsDisordersPsychopathologyBiasSupportRelationshipScaleIndividualsImplicationsSignificant correlationWeight contributes
2011
Metabolic syndrome in obese patients with binge-eating disorder in primary care clinics: a cross-sectional study.
Barnes RD, Boeka AG, McKenzie KC, Genao I, Garcia RL, Ellman MS, Ellis PJ, Masheb RM, Grilo CM. Metabolic syndrome in obese patients with binge-eating disorder in primary care clinics: a cross-sectional study. The Primary Care Companion For CNS Disorders 2011, 13 PMID: 21977358, PMCID: PMC3184595, DOI: 10.4088/pcc.10m01050.Peer-Reviewed Original ResearchBinge-eating disorderMetabolic syndromeObese patientsDietary restrictionDSM-IV-TR research criteriaGeneral internal medicine settingUniversity-based medical centerCertain lifestyle behaviorsCurrent dietary restrictionsPercent of patientsPrimary care clinicsPrimary care settingBody mass indexPrimary care facilitiesCross-sectional studyInternal medicine settingWeight-related correlatesBinge-eating frequencyWeight-related variablesCross-sectional analysisTreatment-seeking obese patientsCare clinicsMass indexLifestyle behaviorsCare settings