Charles B. G. Murphy Professor of Psychiatry and Professor in the Child Study Center, of Neuroscience and of Pharmacology; Director Division of Molecular Psychiatry, Psychiatry; Deputy Chair for Basic Science Research, Dept. of Psychiatry; Director, Interdepartmental Neuroscience Program
TCORS 1.0
Project 1 - Effects of Flavors on Nicotine Choice and Central Reward Mechanisms
Tobacco manufacturers have recently started selling novel tobacco lozenges and other products that resemble candy and minty breath fresheners especially attractive to young consumers. In our proposed studies we will use rodent models to examine whether the minty and sweet candy flavors in these products mask the unpleasant taste of tobacco and promote nicotine addiction.
Research Team
Albert E. Kent Associate Professor of Psychiatry and Associate Professor of Cellular and Molecular Physiology; Director of Scientist Diversity and Inclusion, YSM Office of Diversity, Equity and Inclusion
Associate Professor of Anesthesiology, Pharmacology & Cancer Biology, University Program of Environmental Health (UPEH), Duke University School of Medicine
Project 2 - Menthol’s Effects on the Nicotine Reinforcement in Smokers
This study will address the potential contribution of menthol to nicotine's addictive effects. The results of this study may help to develop science based policies that will reduce the appeal and addictiveness of tobacco products.
Research Team
Professor of Psychiatry; Director of VA New England Mental Illness Research, Education and Clinical Center (MIRECC)
Project 3 - Flavors and E-cigarette Effects in Adolescent Smokers
This study will evaluate the reinforcement efficacy of electronic cigarettes containing menthol and other flavors among adolescent smokers. The results of this study may inform the regulation of constituents in current and future modified risk tobacco products.
Research Team
Albert E. Kent Professor of Psychiatry; Chair, Human Investigations Committee (IRB), Human Research Protections Program; Professor, Chronic Disease Epidemiology
Project 4 - Economics, Experiments and PATH Data: Creating Knowledge for Tobacco Regulation
The overarching aim of this study is to develop the knowledge base for development of effective tobacco regulation to reduce addiction by examining factors that influence the perceptions about, evaluations of, and potential use of e-cigarettes as compared to cigarettes. Using questions coordinated across our experiments and secondary data, we will link our findings to large nationally representative secondary data sets to evaluate modified risk tobacco products and regulations.
Research Team
Professor Emeritus of Public Health; Affiliated Faculty, Yale Institute for Global Health; Research Associate, NBER
- Johanna Catherine Maclean
Assistant Professor of Medical Ethics and Health Policy