2024
A Review of the Toxicity of Ingredients in e-Cigarettes, Including Those Ingredients Having the FDA’s “Generally Recognized as Safe (GRAS)” Regulatory Status for Use in Food
Kassem N, Strongin R, Stroup A, Brinkman M, El-Hellani A, Erythropel H, Etemadi A, Exil V, Goniewicz M, Kassem N, Klupinski T, Liles S, Muthumalage T, Noël A, Peyton D, Wang Q, Rahman I, Valerio L. A Review of the Toxicity of Ingredients in e-Cigarettes, Including Those Ingredients Having the FDA’s “Generally Recognized as Safe (GRAS)” Regulatory Status for Use in Food. Nicotine & Tobacco Research 2024, 26: 1445-1454. PMID: 38783714, PMCID: PMC11494494, DOI: 10.1093/ntr/ntae123.Peer-Reviewed Original ResearchExtract Manufacturers AssociationE-cigarettesE-cigarette productsFood ingredientsFood additivesPrevalence of e-cigarette useGRAS substancesGRASE-liquidsE-cigarette useFoodIngredientsE-cigarette toxicityEvidence of adverse effectsProduct ingredientsToxicity of ingredientsE-liquid ingredientsDrug and Cosmetic ActOral consumptionRegulatory statusElectronic cigarettesChemical compoundsToxicological evaluationProduct labelsRefill liquids
2017
The effect of sucralose on flavor sweetness in electronic cigarettes varies between delivery devices
Rosbrook K, Erythropel HC, DeWinter TM, Falinski M, O’Malley S, Krishnan-Sarin S, Anastas PT, Zimmerman JB, Green BG. The effect of sucralose on flavor sweetness in electronic cigarettes varies between delivery devices. PLOS ONE 2017, 12: e0185334. PMID: 28968411, PMCID: PMC5624589, DOI: 10.1371/journal.pone.0185334.Peer-Reviewed Original ResearchConceptsCommercial e-liquidsDelivery systemConcentrations of sucraloseE-liquid aerosolLC/MSE-liquidsVolatile flavor componentsLiquid delivery systemChemical compoundsChemical analysisArtificial sweetenersE-cigarette designFlavor additivesDelivery devicesVolatile constituentsFlavor componentsSweetener sucraloseVolatile chemicalsSweet aromaCartridge systemSufficient concentrationSucraloseEffect of sucralose