2015
Dopamine/Adenosine Interactions Related to Tremor in Animal Models of Parkinsonism
Salamone J, Podurgiel S, Long L, Nunes E, Correa M. Dopamine/Adenosine Interactions Related to Tremor in Animal Models of Parkinsonism. Current Topics In Neurotoxicity 2015, 10: 149-162. DOI: 10.1007/978-3-319-20273-0_8.Peer-Reviewed Original ResearchAdenosine A2A receptor antagonistTremulous jaw movementsA2A receptor antagonistsAdenosine A2A receptorsAnimal modelsReceptor antagonistA2A receptorsAdenosine A2A receptor knockout miceA2A receptor knockout miceTremulous jaw movement modelAnti-tremor effectJaw movementsReceptor knockout miceHuman clinical studiesAdenosine A2A antagonistsAntiparkinsonian effectsCholinomimetic stimulationOral tremorIntrastriatal injectionDopamine depletionCGS 21680Antiparkinsonian agentsDopamine antagonistsClinical studiesA2A antagonists
2012
The Role of Adenosine in the Ventral Striatal Circuits Regulating Behavioral Activation and Effort-Related Decision Making: Importance for Normal and Pathological Aspects of Motivation
Salamone J, Correa M, Randall P, Nunes E, Pardo M, Lopez-Cruz L. The Role of Adenosine in the Ventral Striatal Circuits Regulating Behavioral Activation and Effort-Related Decision Making: Importance for Normal and Pathological Aspects of Motivation. 2012, 493-512. DOI: 10.1007/978-1-4614-3903-5_23.Peer-Reviewed Original ResearchIntra-accumbens injectionsDA depletionReceptor antagonistAccumbens DA depletionsEffort-related processesAdenosine A2A receptor antagonistA1 receptor antagonistAdenosine A2A agonistDA D2 antagonistsA2A receptor antagonistsRole of adenosineAdenosine A2A receptorsEffort-related decision makingEffort-related choice behaviorBrain dopamineNeuromodulator adenosineD2 antagonistD2 antagonismA2A agonistNucleus accumbensStriatal circuitsTendency of ratsMotivational symptomsA2A receptorsPathological aspects