2010
Inclusion of Women and Gender-Specific Analyses in Randomized Clinical Trials of Treatments for Depression
Weinberger AH, McKee SA, Mazure CM. Inclusion of Women and Gender-Specific Analyses in Randomized Clinical Trials of Treatments for Depression. Journal Of Women's Health 2010, 19: 1727-1732. PMID: 20799923, PMCID: PMC2936499, DOI: 10.1089/jwh.2009.1784.Peer-Reviewed Original ResearchConceptsRecent randomized clinical trialsRandomized clinical trialsClinical trialsGender-specific analysisDepression treatmentHealth (NIH) Revitalization ActCost of depressionInterventional studyInclusion of womenHigh prevalenceTreatment responseMEDLINE searchTreatment efficacyGender differencesPossible gender differencesDepression researchTrialsWomenDepressionNational InstituteRevitalization ActTreatmentFemale participantsOutcomesGender
2007
123I-5-IA-85380 SPECT Imaging of Nicotinic Acetylcholine Receptor Availability in Nonsmokers: Effects of Sex and Menstrual Phase
Cosgrove KP, Mitsis EM, Bois F, Frohlich E, Tamagnan GD, Krantzler E, Perry E, Maciejewski PK, Epperson CN, Allen S, O'Malley S, Mazure CM, Seibyl JP, van Dyck CH, Staley JK. 123I-5-IA-85380 SPECT Imaging of Nicotinic Acetylcholine Receptor Availability in Nonsmokers: Effects of Sex and Menstrual Phase. Journal Of Nuclear Medicine 2007, 48: 1633-1640. PMID: 17873128, DOI: 10.2967/jnumed.107.042317.Peer-Reviewed Original ResearchConceptsRegional brain activityMenstrual cycleNAChR availabilityWomen nonsmokersMenstrual phaseRadiotracer metabolismNicotinic acetylcholine receptor systemSex differencesBrain activityEffects of sexNicotinic acetylcholine receptor availabilitySmoking cessation treatmentMid-luteal phaseAcetylcholine receptor systemPlasma protein bindingTobacco smokingCessation treatmentHealthy menRegional brainHormone levelsPlasma measuresTreatment responseOutcome measuresSPECT scansNonsmokers