1991
A Preliminary, Open Study of the Combination of Fluoxetine and Desipramine for Rapid Treatment of Major Depression
Nelson JC, Mazure CM, Bowers MB, Jatlow PI. A Preliminary, Open Study of the Combination of Fluoxetine and Desipramine for Rapid Treatment of Major Depression. JAMA Psychiatry 1991, 48: 303-307. PMID: 2009031, DOI: 10.1001/archpsyc.1991.01810280019002.Peer-Reviewed Original ResearchConceptsMajor depressionMean changeHamilton Depression Rating Scale scoresDepression Rating Scale scoresCombination of fluoxetineDesipramine plasma levelsRating Scale scoresBeta-adrenergic receptorsOpen studyDesipramine levelsPlasma levelsStandardized doseScale scoreDesipramineDesipramine hydrochlorideRapid treatmentPatientsFluoxetineDrugsWeeksDepressionInpatientsTreatmentRecent studiesSame setting
1984
Drug-Responsive Symptoms in Melancholia
Nelson J, Mazure C, Quinlan D, Jatlow P. Drug-Responsive Symptoms in Melancholia. JAMA Psychiatry 1984, 41: 663-668. PMID: 6732425, DOI: 10.1001/archpsyc.1984.01790180033004.Peer-Reviewed Original ResearchConceptsPlasma desipramine concentrationsTricyclic antidepressant treatmentHamilton Depression ScalePretreatment symptom severityAntidepressant treatmentDesipramine treatmentDesipramine concentrationsDepression ScaleDepressive symptomsSymptomsSymptom severityDesipramine hydrochlorideDrug responseMultiple regression analysisPatientsRegression analysisTreatmentMelancholia