The X-Ray Structure of an Antiparallel Dimer of the Human Amyloid Precursor Protein E2 Domain
Wang Y, Ha Y. The X-Ray Structure of an Antiparallel Dimer of the Human Amyloid Precursor Protein E2 Domain. Molecular Cell 2004, 15: 343-353. PMID: 15304215, DOI: 10.1016/j.molcel.2004.06.037.Peer-Reviewed Original ResearchConceptsMembrane protein precursorsX-ray structureSpectrin familyHeparan sulfate proteoglycanDimer interfaceBiological functionsStructure of E2Protein structureProtein precursorPutative ligandE2 domainContinuous helixExtracellular matrixUnexpected resemblanceAntiparallel dimerSulfate proteoglycanAntiparallel orientationPrecursor presentDomainBindsHelixDimerizationSecond monomerH1 and H7 influenza haemagglutinin structures extend a structural classification of haemagglutinin subtypes
Russell R, Gamblin S, Haire L, Stevens D, Xiao B, Ha Y, Skehel J. H1 and H7 influenza haemagglutinin structures extend a structural classification of haemagglutinin subtypes. Virology 2004, 325: 287-296. PMID: 15246268, DOI: 10.1016/j.virol.2004.04.040.Peer-Reviewed Original ResearchThe Structure and Receptor Binding Properties of the 1918 Influenza Hemagglutinin
Gamblin S, Haire L, Russell R, Stevens D, Xiao B, Ha Y, Vasisht N, Steinhauer D, Daniels R, Elliot A, Wiley D, Skehel J. The Structure and Receptor Binding Properties of the 1918 Influenza Hemagglutinin. Science 2004, 303: 1838-1842. PMID: 14764886, DOI: 10.1126/science.1093155.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsBinding SitesBirdsCrystallography, X-RayHemagglutinin Glycoproteins, Influenza VirusHistory, 20th CenturyHumansHydrogen BondingInfluenza A virusInfluenza, HumanMembrane GlycoproteinsModels, MolecularMolecular Sequence DataProtein ConformationProtein Structure, TertiaryReceptors, VirusSequence AlignmentSialic AcidsSpecies SpecificitySwine