2024
Plasma collagen neoepitopes are associated with multiorgan disease in the ACCESS and GRADS sarcoidosis cohorts
Sand J, Jessen H, Leeming D, Yu S, Lee C, Hu B, Sun Y, Adams T, Pivarnik T, Liu A, Woo S, McGovern J, Fiorini V, Saber T, Higuero-Sevilla J, Gulati M, Kaminski N, Damsky W, Shaw A, Mohanty S, Goobie G, Zhang Y, Herzog E, Ryu C. Plasma collagen neoepitopes are associated with multiorgan disease in the ACCESS and GRADS sarcoidosis cohorts. Thorax 2024, thorax-2023-221095. PMID: 39117421, DOI: 10.1136/thorax-2023-221095.Peer-Reviewed Original ResearchSarcoidosis cohortMultiorgan diseasePRO-C3Interleukin-4Case Control Etiologic Study of SarcoidosisPlasma levels of interleukin-4Alpha-1 antitrypsin deficiencyLevels of interleukin-4Pathogenesis of sarcoidosisC6MC3MHealthy control patientsStudy of sarcoidosisGenomic researchAbnormal extracellular matrixAssociated with dermatological diseaseCollagen degradationScadding stageCorticosteroid useComplex diseasesPRO-C6Control patientsIL-13IL-5IL-9
2022
Innate type 2 immunity controls hair follicle commensalism by Demodex mites
Ricardo-Gonzalez R, Kotas M, O’Leary C, Tenvooren I, Marquez D, Singh K, Damsky W, Liao C, Schroeder A, Cohen J, Fassett M, Lee J, Daniel S, Bittinger K, Diaz R, Fraser J, Ansel K, Spitzer M, Liang H, Locksley R. Innate type 2 immunity controls hair follicle commensalism by Demodex mites. The Journal Of Immunology 2022, 208: 50.39-50.39. DOI: 10.4049/jimmunol.208.supp.50.39.Peer-Reviewed Original ResearchIL-13Hair folliclesDemodex mitesEpithelial hair follicleType 2 cytokinesCalifornia San FranciscoAdaptive immune systemEpithelial cell proliferationImmune checkpointsImmune dysfunctionAcne rosaceaInflammatory cellsIL-4Inflammatory conditionsRobert Wood Johnson FoundationInflammatory programHigh burdenEpithelial proliferationIL-4RACutaneous integrityImmune systemCommensal parasitesAnagen onsetBarrier functionCell proliferation