2009
Analysis of transfusion reactions associated with prestorage‐pooled platelet components
Tormey CA, Sweeney JD, Champion MH, Pisciotto PT, Snyder EL, Wu Y. Analysis of transfusion reactions associated with prestorage‐pooled platelet components. Transfusion 2009, 49: 1242-1247. PMID: 19389029, DOI: 10.1111/j.1537-2995.2009.02128.x.Peer-Reviewed Original ResearchConceptsRandom donor plateletsSingle-donor plateletsTransfusion reactionsPlatelet infusionTransfusion-related acute lung injuryCommon adverse eventsPLT productsAcute lung injuryTertiary care hospitalCases of sepsisAllergic transfusion reactionsTransfusion reaction ratesSignificant differencesAdverse eventsLung injuryCare hospitalVolume overloadFebrile reactionsChi-square analysisTotal infusionPlatelet componentsInfusionStudy designP-valuePlateletsDevelopment of a Humanized Mouse Model to Study the Role of Macrophages in Allograft Injury
Kirkiles-Smith NC, Harding MJ, Shepherd BR, Fader SA, Yi T, Wang Y, McNiff JM, Snyder EL, Lorber MI, Tellides G, Pober JS. Development of a Humanized Mouse Model to Study the Role of Macrophages in Allograft Injury. Transplantation 2009, 87: 189-197. PMID: 19155972, PMCID: PMC2776641, DOI: 10.1097/tp.0b013e318192e05d.Peer-Reviewed Original ResearchMeSH KeywordsAdoptive TransferAdult Stem CellsAnimalsAntigens, CDAntigens, CD34Antigens, Differentiation, MyelomonocyticArteriesDisease Models, AnimalGraft RejectionHematopoietic Stem Cell TransplantationHematopoietic Stem CellsHumansInterleukin Receptor Common gamma SubunitLipopolysaccharide ReceptorsMacrophagesMiceMice, Inbred NODMice, KnockoutMice, SCIDReceptors, Cell SurfaceSkinSkin TransplantationT-LymphocytesTransplantation, HomologousWhole-Body IrradiationConceptsT cellsImmunodeficient micePeripheral blood monuclear cellsHematopoietic stem cellsAllogeneic T cellsHuman cell engraftmentHumanized mouse modelHuman monocytes/macrophagesRole of macrophagesArterial interposition graftsMonocytes/macrophagesImmunodeficient mouse hostsStem cellsHuman skinAllograft injuryArtery graftAdoptive transferInterposition graftPeripheral bloodTransplant rejectionIntimal expansionHuman allograftsMouse modelCell engraftmentTissue graft
2008
Component therapy to cellular therapy and beyond— a Darwinian approach to transfusion medicine
Snyder EL. Component therapy to cellular therapy and beyond— a Darwinian approach to transfusion medicine. Transfusion 2008, 48: 2000-2007. PMID: 18694467, DOI: 10.1111/j.1537-2995.2008.01859.x.Peer-Reviewed Original ResearchMobilization, collection, and transplantation of peripheral blood hematopoietic progenitor cells in a patient with multiple myeloma and hemoglobin SC disease
Tormey CA, Snyder EL, Cooper DL. Mobilization, collection, and transplantation of peripheral blood hematopoietic progenitor cells in a patient with multiple myeloma and hemoglobin SC disease. Transfusion 2008, 48: 1930-1933. PMID: 18513256, DOI: 10.1111/j.1537-2995.2008.01777.x.Peer-Reviewed Original ResearchConceptsHigh-dose G-CSFHemoglobin SC diseaseHematopoietic progenitor cellsHPC mobilizationVasoocclusive crisisSC diseaseG-CSFVasoocclusive complicationsAutologous stem cell transplantationAutologous hematopoietic progenitor cellsPeripheral blood hematopoietic progenitor cellsBlood hematopoietic progenitor cellsProgenitor cellsStem cell transplantationG-CSF administrationG-CSF mobilizationPosttransplant periodMyeloablative chemotherapyCell transplantationMultiple myelomaErythrocytapheresisPatientsCell engraftmentComplicationsBlood harvesting
2007
Successful in vivo recovery and extended storage of additive solution (AS)‐5 red blood cells after deglycerolization and resuspension in AS‐3 for 15 days with an automated closed system
Bandarenko N, Cancelas J, Snyder EL, Hay SN, Rugg N, Corda T, Joines AD, Gormas JF, Pratt GP, Kowalsky R, Rose M, Rose L, Foley J, Popovsky MA. Successful in vivo recovery and extended storage of additive solution (AS)‐5 red blood cells after deglycerolization and resuspension in AS‐3 for 15 days with an automated closed system. Transfusion 2007, 47: 680-686. PMID: 17381627, DOI: 10.1111/j.1537-2995.2007.01171.x.Peer-Reviewed Original Research
2005
Platelet dose consistency and its effect on the number of platelet transfusions for support of thrombocytopenia: an analysis of the SPRINT trial of platelets photochemically treated with amotosalen HCl and ultraviolet A light
Murphy S, Snyder E, Cable R, Slichter SJ, Strauss RG, McCullough J, Lin J, Corash L, Conlan MG, Group T. Platelet dose consistency and its effect on the number of platelet transfusions for support of thrombocytopenia: an analysis of the SPRINT trial of platelets photochemically treated with amotosalen HCl and ultraviolet A light. Transfusion 2005, 46: 24-33. PMID: 16398727, DOI: 10.1111/j.1537-2995.2005.00671.x.Peer-Reviewed Original ResearchConceptsNumber of plateletsTransfusion intervalCount incrementPLT dosePCT plateletsControl groupRed blood cell transfusionSPRINT trialBlood cell transfusionComparison of patientsTransfusion requirementsCell transfusionPCT groupControl patientsPCT patientsRBC transfusionPlatelet transfusionsAmotosalen HClTransfusion responseConventional plateletsPLT transfusionsComparable dosesControl transfusionsTransfusionPatients