Niacin skin flush and membrane polyunsaturated fatty acids in schizophrenia from the acute state to partial remission: a dynamic relationship
Yu Y, Su H, Lin S, Hsiao P, Lin Y, Liu C, Hwang T, Hsieh M, Liu C, Chien Y, Kuo C, Hwu H, Chen W. Niacin skin flush and membrane polyunsaturated fatty acids in schizophrenia from the acute state to partial remission: a dynamic relationship. Schizophrenia 2022, 8: 38. PMID: 35853900, PMCID: PMC9261101, DOI: 10.1038/s41537-022-00252-w.Peer-Reviewed Original ResearchSchizophrenia patientsMembrane polyunsaturated fatty acidsNiacin skin testFlushing responseArachidonic acid levelsArachidonic acidFollow-upIncreased turnover of arachidonic acidSkin testFlush scorePolyunsaturated fatty acidsVulnerability to schizophreniaTurnover of arachidonic acidDihomo-gamma-linolenic acidSchizophrenia inpatientsPartial remissionSchizophreniaAcute exacerbationSkin flushingHealthy controlsControl-to-case ratioPatientsPersistent decreaseDocosahexaenoic acidIncreased turnover