2020
Shortening Velocity Causes Myosin Isoform Shift in Human Engineered Heart Tissues
Ng R, Sewanan LR, Stankey P, Li X, Qyang Y, Campbell S. Shortening Velocity Causes Myosin Isoform Shift in Human Engineered Heart Tissues. Circulation Research 2020, 128: 281-283. PMID: 33183160, PMCID: PMC7855774, DOI: 10.1161/circresaha.120.316950.Peer-Reviewed Original Research
2019
Patient mutations linked to arrhythmogenic cardiomyopathy enhance calpain-mediated desmoplakin degradation
Ng R, Manring H, Papoutsidakis N, Albertelli T, Tsai N, See CJ, Li X, Park J, Stevens TL, Bobbili PJ, Riaz M, Ren Y, Stoddard CE, Janssen PM, Bunch TJ, Hall SP, Lo YC, Jacoby DL, Qyang Y, Wright N, Ackermann MA, Campbell SG. Patient mutations linked to arrhythmogenic cardiomyopathy enhance calpain-mediated desmoplakin degradation. JCI Insight 2019, 5 PMID: 31194698, PMCID: PMC6675562, DOI: 10.1172/jci.insight.128643.Peer-Reviewed Original Research
2016
Tissue-Engineered Vascular Rings from Human iPSC-Derived Smooth Muscle Cells
Dash BC, Levi K, Schwan J, Luo J, Bartulos O, Wu H, Qiu C, Yi T, Ren Y, Campbell S, Rolle MW, Qyang Y. Tissue-Engineered Vascular Rings from Human iPSC-Derived Smooth Muscle Cells. Stem Cell Reports 2016, 7: 19-28. PMID: 27411102, PMCID: PMC4945325, DOI: 10.1016/j.stemcr.2016.05.004.Peer-Reviewed Original ResearchConceptsVascular tissue engineeringFunctional vascular smooth muscle cellsCell-based tissueSelf-assembly approachRenewable sourcesTissue engineeringPluripotent stem cellsPlatform technologyBiomedical applicationsTissue ringsDrug screeningDisease modelingTissue model systemsHuman iPSCStem cellsBroad utilityEfficient approachLarge quantitiesEngineeringMaterials