Histologic patterns of liver injury induced by anti-PD-1 therapy
Zhang D, Hart J, Ding X, Zhang X, Feely M, Yassan L, Alpert L, Soldevila-Pico C, Zhang X, Liu X, Lai J. Histologic patterns of liver injury induced by anti-PD-1 therapy. Gastroenterology Report 2019, 8: 50-55. PMID: 32467761, PMCID: PMC7244961, DOI: 10.1093/gastro/goz044.Peer-Reviewed Original ResearchAnti-PD-1 therapyAnti-PD-1 treatmentLiver function testsHistologic patternAutoimmune hepatitisAdvanced malignanciesLiver injuryAbnormal liver function testsAnti-PD-1 agentsClassical autoimmune hepatitisLiver chemistry testsMultiple advanced malignanciesPD-1 inhibitorsSevere liver injuryCell death 1Different histologic patternsCholestatic injuryHepatitis panelSteroid therapyAbdominal painAcute hepatitisGastrointestinal symptomsImmunosuppressive therapyDrug cessationHistologic injury