Detecting EGFR mutations (L858R, T790M) using allele specific multiplex sequencing: A comparison with Pyrosequencing and TruSeq
Vinayagamoorthy D, Walsh J, Gipson K, Ye F, Zhong M, Dahui Q, Vinayagamoorthy T. Detecting EGFR mutations (L858R, T790M) using allele specific multiplex sequencing: A comparison with Pyrosequencing and TruSeq. Journal Of Solid Tumors 2020, 10: 19. DOI: 10.5430/jst.v10n1p19.Peer-Reviewed Original ResearchEGFR mutationsT790MMultiplex sequencingLate stage lung cancerDetect EGFR mutationsFFPE samplesEGFR somatic mutationsStage lung cancerLow copy numberLung cancer samplesDetect EGFRAnalytical lower limitL858RLung cancerTruSeqCopy numberDetect mutationsPyrosequencingT790EGFRSomatic mutationsCancer samplesMutationsFFPEConcordance