1981
Inhibition by indomethacin of adaptive changes in the contralateral kidney after release of unilateral ureteral occlusion
Siegel N, Upadhyaya K, Kashgarian M. Inhibition by indomethacin of adaptive changes in the contralateral kidney after release of unilateral ureteral occlusion. Kidney International 1981, 20: 691-694. PMID: 7334741, DOI: 10.1038/ki.1981.197.Peer-Reviewed Original ResearchConceptsUnilateral ureteral occlusionBilateral ureteral occlusionContralateral kidneyUreteral occlusionRenal functionAdaptive changesCompensatory changesObstructive renal injuryInfusion of indomethacinRelease of obstructionRenal hemodynamicsRenal injuryPattern of recoveryObstructive nephropathyPathophysiologic alterationsRenal massesUnoperated kidneysKidneyOcclusionAdaptive alterationsHemodynamicsControl organsIndomethacinAlterationsPresent study
1974
Compensatory adaptation of structure and function following progressive renal ablation
Kaufman J, DiMeola H, Siegel N, Lytton B, Kashgarian M, Hayslett J. Compensatory adaptation of structure and function following progressive renal ablation. Kidney International 1974, 6: 10-17. PMID: 4419711, DOI: 10.1038/ki.1974.72.Peer-Reviewed Original ResearchConceptsRenal ablationRenal tissueNephron glomerular filtration rateCompensatory adaptationGlomerular filtration rateClearance of inulinRenal insufficiencyUninephrectomized ratsFour-week intervalsFiltration rateRenal massesGroup BGroup AControl animalsGroup CLE ratsFunctional changesMass of tissueSegmental lossRatsSurgeryAdaptive changesAblationClearanceTissue
1973
Increased tubular reabsorption of sodium in compensatory renal growth
Weinman E, Renquist K, Stroup R, Kashgarian M, Hayslett J. Increased tubular reabsorption of sodium in compensatory renal growth. American Journal Of Physiology 1973, 224: 565-571. PMID: 4691269, DOI: 10.1152/ajplegacy.1973.224.3.565.Peer-Reviewed Original Research
1969
Mechanism of change in the excretion of sodium per nephron when renal mass is reduced
Hayslett J, Kashgarian M, Epstein F. Mechanism of change in the excretion of sodium per nephron when renal mass is reduced. Journal Of Clinical Investigation 1969, 48: 1002-1006. PMID: 5771184, PMCID: PMC322314, DOI: 10.1172/jci106056.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsGlomerular Filtration RateInulinKidneyKidney Failure, ChronicKidney TubulesMaleNephrectomyRatsSodiumConceptsSodium excretionRenal tissueProximal tubular absorptionExcretion of sodiumHealthy nephronsPopulation of nephronsRenal insufficiencyRenal ablationRenal failureTubular absorptionRenal massesSodium balanceGlomerular filtrationDistal tubulesExcretionNephronOsmotic loadEarly adjustmentStepwise increaseMechanisms of changeTissueUninephrectomyHyperfiltrationInsufficiencyRats
1968
Functional correlates of compensatory renal hypertrophy
Hayslett J, Kashgarian M, Epstein F. Functional correlates of compensatory renal hypertrophy. Journal Of Clinical Investigation 1968, 47: 774-782. PMID: 5641618, PMCID: PMC297228, DOI: 10.1172/jci105772.Peer-Reviewed Original Research