Expression and molecular regulation of Na(+)-K(+)-ATPase after renal ischemia
Van Why S, Mann A, Ardito T, Siegel N, Kashgarian M. Expression and molecular regulation of Na(+)-K(+)-ATPase after renal ischemia. American Journal Of Physiology 1994, 267: f75-f85. PMID: 8048568, DOI: 10.1152/ajprenal.1994.267.1.f75.Peer-Reviewed Original ResearchA granulocyte inhibitory protein overexpressed in chronic renal disease regulates expression of interleukin 6 and interleukin 8.
Ziesche R, Roth M, Papakonstantinou E, Nauck M, Hörl W, Kashgarian M, Block L. A granulocyte inhibitory protein overexpressed in chronic renal disease regulates expression of interleukin 6 and interleukin 8. Proceedings Of The National Academy Of Sciences Of The United States Of America 1994, 91: 301-305. PMID: 8278382, PMCID: PMC42935, DOI: 10.1073/pnas.91.1.301.Peer-Reviewed Original ResearchConceptsGranulocyte inhibitory proteinsInterleukin-6Chronic renal diseaseChronic renal failureProgression of glomerulosclerosisHuman mesangial cellsInhibitory proteinPluripotential effectsRenal failureRenal diseaseCytokine expressionIL-6IL-8Interleukin-8Inflammatory reactionGIP resultsGlomerular responseMesangial cellsC-jun mRNAC-fos geneC-JunDe novo synthesisNovo synthesisExpressionOverall effectTransforming growth factor-beta 1 stimulates glomerular mesangial cell synthesis of the 72-kd type IV collagenase.
Marti H, Lee L, Kashgarian M, Lovett D. Transforming growth factor-beta 1 stimulates glomerular mesangial cell synthesis of the 72-kd type IV collagenase. American Journal Of Pathology 1994, 144: 82-94. PMID: 8291614, PMCID: PMC1887110.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBase SequenceBlotting, NorthernCells, CulturedCollagenasesEnzyme-Linked Immunosorbent AssayGlomerular MesangiumHumansImmunohistochemistryMatrix Metalloproteinase 9Molecular ProbesMolecular Sequence DataNephritisRatsRats, WistarTranscription, GeneticTransforming Growth Factor betaConceptsType IV collagenaseHuman mesangial cellsType IVMesangial cellsImmune complex-mediated glomerulonephritisMRNA expressionType IV collagenase mRNA expressionCultured human mesangial cellsCollagenase mRNA expressionMesangial cell synthesisGlomerular inflammatory processesTIMP-1 synthesisNephritic ratsInflammatory processGlomerular matrixMesangial distributionMatrix protein synthesisTIMP-1Direct stimulationTissue inhibitorNormal animalsMesangial compartmentMatrix metalloproteinase synthesisStimulatory effectTIMP-1 inhibitor