1991
Redistribution of cellular energy following renal ischemia
Gaudio K, Thulin G, Ardito T, Kashgarian M, Siegel N. Redistribution of cellular energy following renal ischemia. Pediatric Nephrology 1991, 5: 591-596. PMID: 1911145, DOI: 10.1007/bf00856647.Peer-Reviewed Original Research
1989
Metabolic alterations in proximal tubule suspensions obtained from ischemic kidneys
Gaudio K, Thulin G, Ardito T, Kashgarian M, Siegel N. Metabolic alterations in proximal tubule suspensions obtained from ischemic kidneys. American Journal Of Physiology 1989, 257: f383-f389. PMID: 2551186, DOI: 10.1152/ajprenal.1989.257.3.f383.Peer-Reviewed Original ResearchConceptsProximal tubule suspensionsIschemic injuryTubule suspensionsRenal artery ischemiaVivo ischemic injurySprague-Dawley ratsMin of reflowOxygen consumptionPresence of ouabainBasal O2 consumptionArtery ischemiaIschemic kidneyHistopathological appearanceMetabolic alterationsProximal tubulesControl levelsProtein 1
1988
Metabolic and functional consequences of inhibiting adenosine deaminase during renal ischemia in rats.
Stromski M, van Waarde A, Avison M, Thulin G, Gaudio K, Kashgarian M, Shulman R, Siegel N. Metabolic and functional consequences of inhibiting adenosine deaminase during renal ischemia in rats. Journal Of Clinical Investigation 1988, 82: 1694-1699. PMID: 3263396, PMCID: PMC442739, DOI: 10.1172/jci113782.Peer-Reviewed Original ResearchConceptsPostischemic restorationFunctional recoveryBilateral renal artery occlusionAdenosine deaminaseResidual nucleotide poolRenal artery occlusionEnd of ischemiaMin of ischemiaMin of reflowArtery occlusionAdenine nucleotide poolPostischemic recoveryRenal ischemiaNucleotide poolIschemia resultsUntreated animalsDegradation of ATPIschemiaBasal levelsRenal ATPATP levelsInitial recoveryRatsInsultFunctional consequencesBeneficial effect of thyroxin in the treatment of ischemic acute renal failure
Sutter P, Thulin G, Stromski M, Ardito T, Gaudio K, Kashgarian M, Siegel N. Beneficial effect of thyroxin in the treatment of ischemic acute renal failure. Pediatric Nephrology 1988, 2: 1-7. PMID: 2856365, DOI: 10.1007/bf00870370.Peer-Reviewed Original ResearchConceptsAcute renal failureIschemic acute renal failureRenal failureIschemic controlsNormal salineSaline-treated ischemic controlsBeneficial effectsBetter kidney functionDose of T4Min of reflowT4-treated ratsEffect of thyroxinRenal functionKidney functionNS animalsRenal ischemiaInulin clearanceSaline controlsDay 3Day 7IschemiaT4 animalsRenal ATPCellular mechanismsSignificant increase