1995
Heat-insoluble cryoglobulin in a patient with essential type I cryoglobulinemia and massive cryoglobulin-occlusive glomerulonephritis
Ishimura E, Nishizawa Y, Shoji S, Okumura M, Nishitani H, Kim C, Watanabe Y, Wakasa K, Morii H, Kashgarian M. Heat-insoluble cryoglobulin in a patient with essential type I cryoglobulinemia and massive cryoglobulin-occlusive glomerulonephritis. American Journal Of Kidney Diseases 1995, 26: 654-657. PMID: 7573022, DOI: 10.1016/0272-6386(95)90604-5.Peer-Reviewed Original ResearchConceptsEnd-stage renal failureMonoclonal IgG-kappaType I cryoglobulinemiaOnset of diseaseElectron-dense depositsEssential cryoglobulinemiaRenal failureClinical courseRenal biopsyNephrotic syndromeIgG kappaLower extremitiesCryoglobulinsGelatinous appearanceGlomerular capillariesCryoglobulinemiaGlomerulonephritisInitial onsetBiopsyDiseaseOnsetYears
1981
Steroid-dependent nephrotic syndrome in children: Histopathology and relapses after cyclophosphamide treatment
Siegel N, Gaudio K, Krassner L, McDonald B, Anderson F, Kashgarian M. Steroid-dependent nephrotic syndrome in children: Histopathology and relapses after cyclophosphamide treatment. Kidney International 1981, 19: 454-459. PMID: 7241883, DOI: 10.1038/ki.1981.39.Peer-Reviewed Original ResearchConceptsMinimal change lesionSteroid-dependent nephrotic syndromeIncidence of relapseNephrotic syndromeMesangial proliferationSegmental glomerulosclerosisCyclophosphamide treatmentYears of followupTime of treatmentSustained remissionComplete remissionMore relapsesClinical courseHistologic typeHistopathologic typeCyclophosphamidePatientsBiopsy samplesRelapseLesionsSyndromeGlomerulosclerosisRemissionChildrenTreatment
1980
The importance of nonrenal involvement in hemolytic-uremic syndrome.
Upadhyaya K, Barwick K, Fishaut M, Kashgarian M, Siegel N. The importance of nonrenal involvement in hemolytic-uremic syndrome. Pediatrics 1980, 65: 115-20. PMID: 7355005, DOI: 10.1542/peds.65.1.115.Peer-Reviewed Original Research
1975
Minimal-lesion nephrotic syndrome with early resistance to steroid therapy
Siegel N, Gur A, Krassner L, Kashgarian M. Minimal-lesion nephrotic syndrome with early resistance to steroid therapy. The Journal Of Pediatrics 1975, 87: 377-380. PMID: 1165516, DOI: 10.1016/s0022-3476(75)80639-1.Peer-Reviewed Original ResearchConceptsMinimal lesion nephrotic syndromeNephrotic syndromeLong-term clinical courseEarly resistanceMinimal glomerular lesionsClinical courseSteroid responsivenessClinical outcomesPrompt remissionCyclophosphamide treatmentGlomerular lesionsHistopathologic lesionsPatientsRemissionCyclophosphamideSyndromeTherapyLesionsUltimate outcomeOutcomesChildrenCorticosteroidsPrednisoneRelapseSteroidsClinical Aspects of Bilateral Renal Dysplasia in Children
Gur A, Siegel N, Davis C, Kashgarian M, Hayslett J. Clinical Aspects of Bilateral Renal Dysplasia in Children. Nephron 1975, 15: 50-61. PMID: 236522, DOI: 10.1159/000180492.Peer-Reviewed Original ResearchConceptsBilateral renal dysplasiaRenal dysplasiaClinical featuresClinical aspectsProgressive renal deteriorationLong-term prognosisRenal deteriorationBilateral involvementClinical courseUrinary concentrationsLaurence-MoonBiedl syndromePathogenic mechanismsDysplasiaPaucity of informationPatientsChildrenLarge proportionPrognosisSyndromeImpairment