2021
DNA glycosylase deficiency leads to decreased severity of lupus in the Polb-Y265C mouse model
Paluri SL, Burak M, Senejani AG, Levinson M, Rahim T, Clairmont K, Kashgarian M, Alvarado-Cruz I, Meas R, Cardó-Vila M, Zeiss C, Maher S, Bothwell ALM, Coskun E, Kant M, Jaruga P, Dizdaroglu M, Lloyd R, Sweasy JB. DNA glycosylase deficiency leads to decreased severity of lupus in the Polb-Y265C mouse model. DNA Repair 2021, 105: 103152. PMID: 34186496, PMCID: PMC8635285, DOI: 10.1016/j.dnarep.2021.103152.Peer-Reviewed Original Research
1996
The α3 Isoform Protein of the Na+,K+-ATPase Is Associated With the Sites of Cardiac and Neuromuscular Impulse Transmission
Zahler R, Sun W, Ardito T, Zhang Z, Kocsis J, Kashgarian M. The α3 Isoform Protein of the Na+,K+-ATPase Is Associated With the Sites of Cardiac and Neuromuscular Impulse Transmission. Circulation Research 1996, 78: 870-879. PMID: 8620608, DOI: 10.1161/01.res.78.5.870.Peer-Reviewed Original ResearchConceptsNeuromuscular junctionConduction systemImpulse transmissionIsoform-specific antibodiesSkeletal muscle expressesSkeletal musclePresynaptic motor terminalsCardiac conduction systemHeart conduction systemAlpha subunitAxonal processesRat heartCardiac myocytesIsoform mRNAsMuscleClassic morphologyJunctional complexesImmunoreactive proteinPump isoformsAntibodiesIsoform proteinsHeartPump proteinImmunohistochemistryIsoforms
1993
Transport defects of rabbit inner medullary collecting duct cells in obstructive nephropathy
Hwang S, Harris H, Otuechere G, Yalla S, Sullivan M, Kashgarian M, Benos D, Kleyman T, Zeidel M. Transport defects of rabbit inner medullary collecting duct cells in obstructive nephropathy. American Journal Of Physiology 1993, 264: f808-f815. PMID: 8388652, DOI: 10.1152/ajprenal.1993.264.5.f808.Peer-Reviewed Original ResearchConceptsObstructed kidneysIMCD cellsUntreated control kidneysOuabain-insensitive QO2Ouabain-sensitive QO2Urinary obstructionObstructive nephropathyControl kidneysControl animalsControl groupKidneyMonoclonal antibodiesMarked reductionDuct cellsAlpha 1Cellular mechanismsSignificant differencesChannel proteinsReabsorptionAntibodiesOxygen consumption studiesTransport defectRabbitsCellsImmunoblot
1985
Monoclonal antibody to Na,K-ATPase: Immunocytochemical localization along nephron segments
Kashgarian M, Biemesderfer D, Caplan M, Forbush B. Monoclonal antibody to Na,K-ATPase: Immunocytochemical localization along nephron segments. Kidney International 1985, 28: 899-913. PMID: 3003443, DOI: 10.1038/ki.1985.216.Peer-Reviewed Original ResearchConceptsMonoclonal antibodiesNephron segmentsEvidence of labellingRenal tubular epithelial cellsTubular epithelial cellsK-ATPaseThick ascending limbOnly principal cellsDifferent nephron segmentsDog antigensBasal-lateral membranesSignificant antibodiesAscending limbMesangial regionHenle's loopOccasional cellsRenal medullaOuter renal medullaAbundant antibodyAntibodiesApical labelingTubule segmentsPrincipal cellsEpithelial cellsImmunocytochemical localization
1974
SHWARTZMAN REACTION IN AN HL-A-IDENTICAL RENAL ALLOGRAFT
SCHIFF M, GOFFINET J, HENDLER E, RUDDLE N, Kashgarian M, LYTTON B. SHWARTZMAN REACTION IN AN HL-A-IDENTICAL RENAL ALLOGRAFT. Transplantation 1974, 17: 580-583. PMID: 4208389, DOI: 10.1097/00007890-197406000-00006.Peer-Reviewed Original ResearchConceptsShwartzman reactionDiffuse intravascular coagulationIdentical sibling donorsEvidence of sensitizationAntigen mismatchesRenal allograftsIntravascular coagulationKidney transplantSibling donorsNegative bacteremiaHistological examinationSkin transplantationIrreversible cessationSame donorTransplantAllograftsPatientsTransplantationKidneyBacteremiaSteroidsDonorsAntibodiesSensitizationCessation