2000
Interferon-γ elicits arteriosclerosis in the absence of leukocytes
Tellides G, Tereb D, Kirkiles-Smith N, Kim R, Wilson J, Schechner J, Lorber M, Pober J. Interferon-γ elicits arteriosclerosis in the absence of leukocytes. Nature 2000, 403: 207-211. PMID: 10646607, DOI: 10.1038/35003221.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnimalsArteriosclerosisCell DivisionCells, CulturedCoronary VesselsHistocompatibility AntigensHumansImage Processing, Computer-AssistedImmunohistochemistryInterferon-gammaLeukocytesMiceMice, SCIDMuscle, Smooth, VascularPlatelet-Derived Growth FactorReceptor, Platelet-Derived Growth Factor betaSwineTransplantation, HeterologousConceptsVascular smooth muscle cellsGraft arteriosclerosisIntimal expansionAbsence of leukocytesLesions of atherosclerosisSmooth muscle cellsAllogeneic transplantationArteriosclerotic changesAtheroma formationCytokine interferonExogenous IFNAntigen presentationT cellsImmunodeficient miceMononuclear leukocytesMouse modelArterial intimaIFNMuscle cellsArteriosclerosisLeukocytesHuman arteriesAtherosclerosisCellsTransplantation
1999
Immunobiology of human vascular endothelium
Pober J. Immunobiology of human vascular endothelium. Immunologic Research 1999, 19: 225-232. PMID: 10493176, DOI: 10.1007/bf02786490.Peer-Reviewed Original ResearchConceptsVascular endothelial cellsEndothelial cellsImmune reactionsCell-mediated immune reactionsPeptide-major histocompatibility complex complexesImmune effector mechanismsMemory T cellsSecondary immune reactionT cell signalsConsequences of infectionHuman vascular endotheliumHuman T lymphocytesHuman tissue specimensAllograft rejectionIntravascular coagulationAllogeneic transplantationEffector cellsNew effector functionsEffector mechanismsLeukocyte recruitmentImmune surveillanceT cellsT lymphocytesPeripheral tissuesEffector functions