Nitric oxide and vascular remodeling modulate hepatic arterial vascular resistance in the isolated perfused cirrhotic rat liver
Zipprich A, Loureiro-Silva MR, Jain D, D’Silva I, Groszmann RJ. Nitric oxide and vascular remodeling modulate hepatic arterial vascular resistance in the isolated perfused cirrhotic rat liver. Journal Of Hepatology 2008, 49: 739-745. PMID: 18804307, DOI: 10.1016/j.jhep.2008.06.027.Peer-Reviewed Original ResearchConceptsHepatic arterial resistanceArterial resistanceSmooth muscle nucleiL-NMMAHepatic arterial vascular resistanceArterial vascular resistanceMuscle nucleiCirrhotic rat liverRole of NODose-response curveVascular resistanceHepatic arteryArterial remodelingCirrhotic modelVascular remodelingHepatic arteriolesCirrhosisMethoxamineNitric oxideWall thicknessRat liverArteryBDLMain modulatorRemodelingAdult nesidioblastosis. Clinicopathologic correlation between pre-operative selective arterial calcium stimulation studies and post-operative pathologic findings.
Kenney B, Tormey CA, Qin L, Sosa JA, Jain D, Neto A. Adult nesidioblastosis. Clinicopathologic correlation between pre-operative selective arterial calcium stimulation studies and post-operative pathologic findings. JOP Journal Of The Pancreas 2008, 9: 504-11. PMID: 18648143.Peer-Reviewed Original ResearchConceptsDifferential diagnosisDiffuse islet cell hyperplasiaPost-operative pathologic findingsMarked insulin releaseSevere hyperinsulinemic hypoglycemiaIslet cell hyperplasiaCase of nesidioblastosisIslet cell proliferationPancreatic ductal epitheliumRoutine diagnostic laboratoryFactitious hypoglycemiaRadiological findingsSevere hypoglycemiaSubtotal pancreatectomyPathologic findingsAdult nesidioblastosisCell hyperplasiaClinicopathologic correlationPancreatic segmentsDuctal epitheliumHyperinsulinemic hypoglycemiaCalcium challengeHistologic examinationLaboratory examinationsPartial pancreatectomy