2022
An Expert, Multidisciplinary Perspective on Best Practices in Biomarker Testing in Intrahepatic Cholangiocarcinoma
Madoff DC, Abi-Jaoudeh N, Braxton D, Goyal L, Jain D, Odisio BC, Salem R, Schattner M, Sheth R, Li D. An Expert, Multidisciplinary Perspective on Best Practices in Biomarker Testing in Intrahepatic Cholangiocarcinoma. The Oncologist 2022, 27: 884-891. PMID: 35925597, PMCID: PMC9526481, DOI: 10.1093/oncolo/oyac139.Peer-Reviewed Original ResearchMeSH KeywordsBile Duct NeoplasmsBile Ducts, IntrahepaticBiomarkersCholangiocarcinomaHumansPrecision MedicineConceptsIntrahepatic cholangiocarcinomaBiomarker testingMultidisciplinary teamImage-guided liver biopsyMetastatic intrahepatic cholangiocarcinomaEvidence-based guidelinesIntrahepatic biliary treeNext-generation sequencingActionable genetic alterationsTreatment landscapeLiver biopsyMedical oncologistsInterventional oncologistsPoor prognosisAggressive malignancyBiliary treeTissue acquisitionBiopsy methodImaging modalitiesDesmoplastic natureGenetic alterationsTissue collectionNeedle choicePrecision medicineCholangiocarcinoma
2019
In vivo dynamics of T cells and their interactions with dendritic cells in mouse cutaneous graft-versus-host disease
Morin-Zorman S, Wysocki C, Zhu J, Li H, Zorman S, Matte-Martone C, Kisanga E, McNiff J, Jain D, Gonzalez D, Rothstein DM, Lakkis FG, Haberman A, Shlomchik WD. In vivo dynamics of T cells and their interactions with dendritic cells in mouse cutaneous graft-versus-host disease. Blood Advances 2019, 3: 2082-2092. PMID: 31296496, PMCID: PMC6650737, DOI: 10.1182/bloodadvances.2019000227.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBiomarkersCD11c AntigenCell CommunicationDendritic CellsDisease Models, AnimalFluorescent Antibody TechniqueGene ExpressionGenes, ReporterGraft vs Host DiseaseHematopoietic Stem Cell TransplantationHistocompatibility Antigens Class IImmunophenotypingLymphocyte DepletionMiceMice, TransgenicProtein BindingReceptors, Antigen, T-CellSkin DiseasesT-Lymphocyte SubsetsT-LymphocytesTransplantation, HomologousConceptsDonor dendritic cellsCD8 cellsT cellsGVHD lesionsHost diseaseCD4 cellsDendritic cellsAllogeneic hematopoietic stem cell transplantationHematopoietic stem cell transplantationMajority of CD4Dynamics of CD4Stem cell transplantationCutaneous graftAntibody infusionCell transplantationMyeloid cellsIntravital microscopyAcute deletionMajor causeLesionsTarget tissuesCD103CD4InfusionMHCII
2012
Reticulin Loss in Benign Fatty Liver
Singhi AD, Jain D, Kakar S, Wu TT, Yeh MM, Torbenson M. Reticulin Loss in Benign Fatty Liver. The American Journal Of Surgical Pathology 2012, 36: 710-715. PMID: 22498821, DOI: 10.1097/pas.0b013e3182495c73.Peer-Reviewed Original ResearchConceptsLoss of reticulinFatty changeHepatic adenomaHepatocellular carcinomaReticulin stainingDiagnostic pitfallsImportant diagnostic pitfallMarked steatosisModerate steatosisNonalcoholic steatohepatitisMild steatosisFibrosis stageReticulin stainNumber of fociLiver tissueBenign fatty liverCases of steatohepatitisDegree of steatosisDegree of inflammationNon-neoplastic liver tissueAmount of steatosisMarked fatty changeCases of steatosisFine needle aspiratesFatty liver
2008
Identification of lymphatics within the colonic lamina propria in inflammation and neoplasia using the monoclonal antibody D2-40.
Kenney BC, Jain D. Identification of lymphatics within the colonic lamina propria in inflammation and neoplasia using the monoclonal antibody D2-40. The Yale Journal Of Biology And Medicine 2008, 81: 103-13. PMID: 18827885, PMCID: PMC2553648.Peer-Reviewed Original Research
2004
Benign Fibroblastic Polyps of the Colon
Eslami-Varzaneh F, Washington K, Robert ME, Kashgarian M, Goldblum JR, Jain D. Benign Fibroblastic Polyps of the Colon. The American Journal Of Surgical Pathology 2004, 28: 374-378. PMID: 15104300, DOI: 10.1097/00000478-200403000-00010.Peer-Reviewed Original ResearchConceptsMucosal polypsHyperplastic polypsInflammatory fibroid polypGastrointestinal stromal tumorsSpindle cell proliferationBland spindled cellsPanel of antibodiesSmooth muscle actinBenign fibroblastic polypsAssociated adenomasFibroid polypEndoscopic findingsStromal polypsClinicopathologic featuresStromal tumorsSparse cytoplasmic organellesImmunohistochemical findingsFibroblastic featuresNeural tumorsFocal reactivityPolyposis syndromeSpindled cellsMuscularis mucosaeSpindle cellsLamina propria