2021
Obeticholic Acid Decreases Intestinal Content of Enterococcus in Rats With Cirrhosis and Ascites
Yan K, Hung A, Parmer C, Yang H, Jain D, Lim B, Goodman AL, Garcia‐Tsao G. Obeticholic Acid Decreases Intestinal Content of Enterococcus in Rats With Cirrhosis and Ascites. Hepatology Communications 2021, 5: 1507-1517. PMID: 34510838, PMCID: PMC8435275, DOI: 10.1002/hep4.1740.Peer-Reviewed Original ResearchHigher serum albuminBacterial translocationObeticholic acidEnd of studyAspartate aminotransferaseLymph nodesIntestinal microbiomeIntestinal contentsSemisynthetic bile acidMesenteric lymph nodesEnd of treatmentCarbon tetrachloride inhalationExtra-intestinal sitesLower aspartate aminotransferaseFurther decompensationLiver injuryLiver functionPolymerase chain reactionExperimental cirrhosisPathogenic bacteriaCirrhosisHepatocyte deathDay 1Bile acidsPlacebo
2004
Rapid Progression of Autoimmune Hepatitis in the Background of Primary Sclerosing Cholangitis
Hong-Curtis J, Yeh M, Jain D, Lee JH. Rapid Progression of Autoimmune Hepatitis in the Background of Primary Sclerosing Cholangitis. Journal Of Clinical Gastroenterology 2004, 38: 906-909. PMID: 15492611, DOI: 10.1097/00004836-200411000-00015.Peer-Reviewed Original ResearchConceptsPrimary sclerosing cholangitisAutoimmune hepatitisOverlap syndromeSclerosing cholangitisLiver diseaseHemolytic anemiaAIH/PSC overlap syndromePrompt recoveryDiagnosis of AIHPatient's prompt recoveryAutoimmune liver diseaseAutoimmune hemolytic anemiaProgressive liver failurePrimary biliary cirrhosisAcidophil bodiesAutoimmune cholangitisInterface hepatitisImmunosuppressive therapyBiliary cirrhosisLiver biopsyLiver failureLymphoplasmacytic infiltrateUlcerative colitisClinical symptomsLiver function