2022
Prominent Pseudoacini in Focal Nodular Hyperplasia
Wang D, González IA, Russo PA, Jain D, Zhang X. Prominent Pseudoacini in Focal Nodular Hyperplasia. The American Journal Of Surgical Pathology 2022, 46: 1380-1385. PMID: 35749760, DOI: 10.1097/pas.0000000000001931.Peer-Reviewed Original ResearchConceptsFocal nodular hyperplasiaHepatocellular carcinomaNodular hyperplasiaFNH casesPotential diagnostic pitfallInspissated bileChronic cholestasisInitial biopsyPathologic featuresClinicopathologic correlationDiagnostic challengeNeedle biopsyDifferential diagnosisHepatocellular neoplasmsHepatocellular adenomaDiagnostic pitfallsMorphologic featuresLobular parenchymaStaining patternPseudoaciniBiliary transdifferentiationBiopsyHyperplasiaLesionsHepatocytes
2018
Subacute liver failure due to autochthonous hepatitis E virus infection in an elderly man in the United States
Landry M, Kamili S, Jain D. Subacute liver failure due to autochthonous hepatitis E virus infection in an elderly man in the United States. Human Pathology Reports 2018, 12: 68-70. DOI: 10.1016/j.ehpc.2018.02.007.Peer-Reviewed Original ResearchHepatitis E virus infectionE virus infectionLiver failureElderly menDifferential diagnosisVirus infectionToxic injuryAutochthonous hepatitis E virus infectionAutochthonous hepatitis EAcute hepatitis CAnti-HEV IgMHistologic differential diagnosisANA positivityPanlobular hepatitisSubsequent serologyCholestatic hepatitisHepatitis CHepatitis EBiliary obstructionLiver biopsyImmunocompetent individualsFatal outcomeGenotype 3Early diagnosisAppropriate managementA practical diagnostic approach to hepatic masses.
Vyas M, Jain D. A practical diagnostic approach to hepatic masses. Indian Journal Of Pathology And Microbiology 2018, 61: 2-17. PMID: 29567877, DOI: 10.4103/ijpm.ijpm_578_17.Peer-Reviewed Original ResearchConceptsDifferential diagnosisHepatic massCorrect diagnosisRight diagnosisBackground liver diseaseUnknown primary siteFocal nodular hyperplasiaHepatic mass lesionsPractical diagnostic approachList of antibodiesNonhepatocellular originProper workupClinical presentationHepatocellular originLiver diseaseHistologic featuresPrimary lesionClinicopathological correlationHepatic adenomaVascular tumorsMass lesionNonepithelial neoplasmsCommon siteNeedle biopsyNodular hyperplasia
2013
Diagnostic Approach to Hepatic Mass Lesions and Role of Immunohistochemistry
Marginean EC, Gown AM, Jain D. Diagnostic Approach to Hepatic Mass Lesions and Role of Immunohistochemistry. Surgical Pathology Clinics 2013, 6: 333-365. PMID: 26838978, DOI: 10.1016/j.path.2013.03.005.Peer-Reviewed Original ResearchFocal nodular hyperplasiaHepatic mass lesionsMass lesionHepatocellular carcinomaHepatic adenomaDifferential diagnosisDiagnostic approachCommon mass lesionsPrimary hepatic neoplasmsRole of immunohistochemistryCommon malignant tumorPractical diagnostic approachYounger patientsHepatic massMacroregenerative nodulesNoncirrhotic liverNodular hyperplasiaCirrhotic liverImmunohistochemical stainsMalignant tumorsHepatic neoplasmsMalignant lesionsClinical practiceDysplastic nodulesLesionsPediatric Cholestatic Disorders Approach to Pathologic Diagnosis
Morotti RA, Jain D. Pediatric Cholestatic Disorders Approach to Pathologic Diagnosis. Surgical Pathology Clinics 2013, 6: 205-225. PMID: 26838972, DOI: 10.1016/j.path.2013.03.001.Peer-Reviewed Original ResearchLiver diseaseDiagnostic challengePediatric cholestatic disordersClinical featuresPediatric groupHistopathologic featuresCholestatic disordersHistopathologic findingsPathologic diagnosisDifferential diagnosisDiagnostic modalitiesBile synthesisMolecular abnormalitiesDiagnosisDiseaseDisordersSignificant overlapPathophysiologyMolecular geneticsAbnormalities
2012
Inflammatory Disorders of the Large Intestine
Jain D, Warren B, Riddell R. Inflammatory Disorders of the Large Intestine. 2012, 552-635. DOI: 10.1002/9781118399668.ch35.Peer-Reviewed Original ResearchChronic inflammatory bowel diseaseAcute infectious colitisLarge intestinal biopsiesInflammatory bowel diseaseInfection-related conditionsMain infectious agentsDiagnosis of dysplasiaDiagnosis of inflammationInfectious colitisTransplant recipientsVariety of virusesBowel diseaseIntestinal biopsiesInflammatory lesionsInflammatory disordersChronic conditionsDisease burdenEnteric infectionsDifferential diagnosisFrequent causeRare diseaseSpecific diagnosisInfectious agentsImmune systemLarge intestine
2008
Diagnostic approach to needle biopsies of hepatic mass lesions
Mitchell K, Jain D. Diagnostic approach to needle biopsies of hepatic mass lesions. Diagnostic Histopathology 2008, 14: 598-608. DOI: 10.1016/j.mpdhp.2008.09.004.Peer-Reviewed Original ResearchAdult nesidioblastosis. Clinicopathologic correlation between pre-operative selective arterial calcium stimulation studies and post-operative pathologic findings.
Kenney B, Tormey CA, Qin L, Sosa JA, Jain D, Neto A. Adult nesidioblastosis. Clinicopathologic correlation between pre-operative selective arterial calcium stimulation studies and post-operative pathologic findings. JOP Journal Of The Pancreas 2008, 9: 504-11. PMID: 18648143.Peer-Reviewed Original ResearchConceptsDifferential diagnosisDiffuse islet cell hyperplasiaPost-operative pathologic findingsMarked insulin releaseSevere hyperinsulinemic hypoglycemiaIslet cell hyperplasiaCase of nesidioblastosisIslet cell proliferationPancreatic ductal epitheliumRoutine diagnostic laboratoryFactitious hypoglycemiaRadiological findingsSevere hypoglycemiaSubtotal pancreatectomyPathologic findingsAdult nesidioblastosisCell hyperplasiaClinicopathologic correlationPancreatic segmentsDuctal epitheliumHyperinsulinemic hypoglycemiaCalcium challengeHistologic examinationLaboratory examinationsPartial pancreatectomy
2004
Lymphoplasmacytic sclerosing pancreato-cholangitis: a case report and review of the literature.
Prasad P, Salem RR, Mangla R, Aslanian H, Jain D, Lee J. Lymphoplasmacytic sclerosing pancreato-cholangitis: a case report and review of the literature. The Yale Journal Of Biology And Medicine 2004, 77: 143-8. PMID: 15989743, PMCID: PMC2259126.Peer-Reviewed Original ResearchConceptsChronic pancreatitisAutoimmune pancreatitisPancreatic ductNon-alcoholic duct-destructive chronic pancreatitisDuct-destructive chronic pancreatitisPylorus-preserving Whipple procedureBenign formLymphoplasmacytic inflammatory infiltratePrimary sclerosing cholangitisBiliary tract diseaseAbdominal painObliterative phlebitisAutoimmune processSclerosing cholangitisWhipple procedureInflammatory infiltrateInterstitial fibrosisClinical entityCase reportTract diseasePancreatic adenocarcinomaDifferential diagnosisPancreatic carcinomaPancreaticobiliary diseasesPathological overlap